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Table 3 Patients characteristics at time of thrombolysis and 24 hours after thrombolysis

From: Mobilization after thrombolysis (rtPA) within 24 hours of acute stroke: what factors influence inclusion of patients in A Very Early Rehabilitation Trial (AVERT)?

Variable

potAVERT (n = 105)

AVERT (n = 50)

Effect size* (95%CI)

p

Stroke to needle (min)

      

Median (IQR)

138

(108–156)

126

(108–156)

−1.2 (−15-13.2)

0.88

NIHSS

      

At 24 hours

      

Median (IQR)

5.5

(2–12)

8.5

(5–14)

2 (0–5)

0.04

Physiological data at thrombolysis

      

Hypertension

31

(62%)

66

(63%)

0.96 (0.48-1.92)

>0.99

Hypotension

0

0

1

(2.0%)

N/A

0.32

Hyperglycaemia

3

(3.3%)

2

(4.6%)

1.41 (0–7.38)

0.66

Hypoglycaemia

0

0

2

(4.6%)

N/A

0.10

Bradycardia

13

(12%)

10

(20%)

1.77 (0.73-4.30)

0.23

Tachycardia

9

(8.6%)

4

(8.0%)

0.93 (0.29-3.01)

>0.99

Arythmia

24

(25%)

15

(33%)

1.48 (0.69-3.18)

0.32

Rapid atrial fibrillation

5

(4.9%)

3

(6.0%)

1.24 (0.31-4.92)

0.72

Hypoxia

1

(1.0%)

0

0

N/A

>0.99

Complications at 24 h post thrombolysis

      

Hemorrhagic transformation

14

(13%)

10

(20%)

1.63 (0.68-3.91)

0.34

sICH

0

0

1

(2.0%)

N/A

0.32

Bleeding other than cerebral

12

(11%)

3

(6.0%)

0.49 (0.14-1.7)

0.39

DVT

1

(1.0%)

1

(2.0%)

2.12 (0)

0.54

Infection

9

(8.6%)

6

(12%)

1.45 (0.51-4.19)

0.56

  1. *Effect sizes expressed as H-L for continuous and OR for binary.
  2. Hypertension is defined as a blood pressure (BP) > 140/90 mmHg; hypotension: BP < 90/60 mmHg; hyperglycaemia; blood sugar level (BSL) > 13.5 mmol/L; hypoglycaemia: BSL < 4.0 mmol/L; bradycardia: heart rate < 60 beats per minute (bpm); tachycardia > 100 bpm; hypoxia: O2 saturation < 90%.