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Table 4 MRI volume of brain areas in patients with amnestic mild cognitive impairment or early Alzheimer's disease, where patients have been subgrouped according to odor identification (OI) ability

From: The brain structural and cognitive basis of odor identification deficits in mild cognitive impairment and Alzheimer's disease

 

B-SIT

SSIT

Brain areas

Patients

Patients

 

>50% score n = 6 mean ± SD

≤50% score n = 12 mean ± SD

>50% score n = 10 mean ± SD

≤50% score n = 6 mean ± SD

Hemispheric white matter

28.72 ± 2.49

29.40 ± 1.94

28.75 ± 1.96

30.49 ± 2.06

Cortical grey matter

27.77 ± 1.77

28.06 ± 1.25

28.15 ± 1.25

26.49 ± 2.46

Hippocampus

0.45 ± 0.02

0.41 ± 0.04a

0.44 ± 0.02

0.38 ± 0.04a

Amygdala

0.22 ± 0.04

0.18 ± 0.02

0.21 ± 0.03

0.17 ± 0.03a

Thalamus

1.10 ± 0.07

1.10 ± 0.08

1.13 ± 0.07

1.20 ± 0.56

Total venticular volume

0.86 ± 0.16

0.65 ± 0.22

0.81 ± 0.24

0.72 ± 0.18

  1. aSignificant difference between patients subgrouped as having > 50% or ≤ 50% score according to either the Brief Smell Identification Test (B-SIT), or Sniffin Sticks Identification Test (SSIT), p < 0.017.