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Table 4 MRI volume of brain areas in patients with amnestic mild cognitive impairment or early Alzheimer's disease, where patients have been subgrouped according to odor identification (OI) ability

From: The brain structural and cognitive basis of odor identification deficits in mild cognitive impairment and Alzheimer's disease

  B-SIT SSIT
Brain areas Patients Patients
  >50% score n = 6 mean ± SD ≤50% score n = 12 mean ± SD >50% score n = 10 mean ± SD ≤50% score n = 6 mean ± SD
Hemispheric white matter 28.72 ± 2.49 29.40 ± 1.94 28.75 ± 1.96 30.49 ± 2.06
Cortical grey matter 27.77 ± 1.77 28.06 ± 1.25 28.15 ± 1.25 26.49 ± 2.46
Hippocampus 0.45 ± 0.02 0.41 ± 0.04a 0.44 ± 0.02 0.38 ± 0.04a
Amygdala 0.22 ± 0.04 0.18 ± 0.02 0.21 ± 0.03 0.17 ± 0.03a
Thalamus 1.10 ± 0.07 1.10 ± 0.08 1.13 ± 0.07 1.20 ± 0.56
Total venticular volume 0.86 ± 0.16 0.65 ± 0.22 0.81 ± 0.24 0.72 ± 0.18
  1. aSignificant difference between patients subgrouped as having > 50% or ≤ 50% score according to either the Brief Smell Identification Test (B-SIT), or Sniffin Sticks Identification Test (SSIT), p < 0.017.