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Table 1 Socio-demographic and clinical characteristics ( n = 681)

From: Response to cholinesterase inhibitors affects lifespan in Alzheimer's disease

Variable

 

Female sex

423 (62%)

APOE ε4 carrier, (n = 667)

437 (66%)

Solitary living at baseline

240 (35%)

Antihypertensives/cardiac therapy

289 (42%)

Antidiabetics

30 (4%)

Lipid-lowering agents

63 (9%)

Estrogens

51 (7%)

NSAIDs/acetylsalicylic acid

212 (31%)

Antidepressants

174 (26%)

Antipsychotics

30 (4%)

Anxiolytics/sedatives/hypnotics

92 (14%)

Variable

Mean ± standard deviation

Estimated age at onset (years)

73.0 ± 6.9

Estimated duration of AD at baseline (years)

3.1 ± 2.0

Age at first assessment (years)

76.1 ± 6.5

Education (years)

9.3 ± 2.4

Age at death (years)

81.9 ± 6.6

MMSE score at baseline

20.9 ± 3.9

ADAS-cog score (0-70) at baseline

22.0 ± 9.1

IADL score at baseline

16.6 ± 5.4

PSMS score at baseline

7.7 ± 2.3

Number of concomitant medications at baseline

3.0 ± 2.5

  1. Abbreviations: ADAS-cog Alzheimer's Disease Assessment Scale-cognitive subscale, APOE apolipoprotein E, IADL Instrumental Activities of Daily Living scale, MMSE Mini-Mental State Examination, NSAIDs nonsteroidal anti-inflammatory drugs; PSMS, Physical Self-Maintenance Scale.