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Table 1 Comparison between patients with prescription for anticoagulants versus without

From: Secondary stroke prevention in atrial fibrillation: a challenge in the clinical practice

  Total cohort Prescription for OA Non-Prescription for OA P OR* (95% CI)
(n = 1.828) 100% (n = 827) 45,24% (n = 1.001) 54,76%
Age (years) median/mean (SD) 77.61 (±8.6) 75.01 (±8.1) 79.75 (±8.5) < 0.001  
  < 65 years 126 (6.9%) 79 (9.6%) 47 (4.7%) < 0.001 2.14 (1.48-3.11)
  65-75 years 537 (29.4%) 323 (39.1%) 214 (21.4%) < 0.001 2.36 (1.99-2.90)
  > 75 years 1165 (63.7%) 425 (51.4%) 740 (73.9%) < 0.001 0.37 (0.31-0.45)
Sex      
  Male 764 (41.8%) 398 (48.1%) 366 (36.6%) < 0.001 ref. category
  Female 1064 (58.2%) 429 (51.9%) 635 (63.4%) < 0.001 0.62 (0.52-0.75)
Risk factors      
  Hypertension 1444 (79.0%) 660 (79.8%) 784 (78.3%) 0.4 1.09 (0.87-1.37)
  Diabetes mellitus 530 (29.0%) 240 (29.0%) 290 (29.0%) 0.9 1.00 (0.82-1.23)
Diagnosis      
  TIA 639 (35.0%) 260 (31.4%) 379 (37.9%) < 0.001 0.75 (0.62-0.91)
 Previous stroke 433 (23.7%) 179 (21.6%) 254 (25.4%) 0.062 0.81 (0.65-1.01)
mRS as assessed on discharge      
  0 557 (30.5%) 282 (34.1%) 275 (27.5%) 0.002 1.37 (1.19-1.67)
  1 478 (26.1%) 226 (27.3%) 252 (25.2%) 0.3 1.18 (0.91-1.38)
  2 403 (22.0%) 174 (21.0%) 229 (22.9%) 0.3 0.90 (0.72-1.12)
  3 390 (21.3%) 145 (17.5%) 245 (24.5%) < 0.001 0.66 (0.52-0.82)
  Median, range 1 (0-3) 1 (0-3) 1 (0-3)   
Treatment in a neurological department 1243 (68.0%) 611 (73.9%) 632 (63.1%) < 0.001 1.65 (1.35-2.02)
Comorbidities occurring while hospitalisation      
  Intracranial bleeding 8 (0.4%) 5 (0.6%) 3 (0.3%) 0.3 2.02 (0.48-8.49)
  Extracranial bleeding 7 (0.4%) 4 (0.5%) 3 (0.3%) 0.5 1.61 (0.36-7.24)
  Recurrent stroke/TIA 17 (0.9%) 12 (1.5%) 5 (0.5%) 0.04 2.93 (1.03-8.36)
  Seizure 6 (0.3%) 0 (0%) 6 (0.6%) 0.03 not applicable
  Pneumonia 42 (2.3%) 18 (2.2%) 24 (2.4%) 0.8 0.91 (0.49-1.69)
Documented dementia within the insurance database # 241 (13.2%) 67 (7.2%) 174 (14.2%) < 0.001 0.42 (0.31-0.56)
  1. *Value calculated in a Chi Square Test of Independence.
  2. #dementia documented within the insurance database on discharge or within 90 days after discharge; considered were the following ICD10 codes: dementia by Alzheimer's disease (F00.-), vascular dementia (F01.-, G30), secondary dementia (F02.-) and undetermined dementia (F.03).
  3. AK refers to anticoagulants.
  4. TIA refers to transient ischaemic attack.
  5. mRS refers to modified Rankin scale.