From: Hypopituitarism after subarachnoid haemorrhage, do we know enough?
 | Study design | Inclusion criteria | Exclusion criteria | Selection bias | Lost to FU nr | Dynamic tests | Analysis | Results |
---|---|---|---|---|---|---|---|---|
Aimaretti et al. [37] | Prospective cohort | - | - | yes | 0 | GHRH-arg | + | + |
Brandt et al. [33] | Case series | + | + | yes | 0 | TRH test & ITT (7 out of 10 pts) | + | + |
Dimopoulou et al. [17] | Retrospective cohort | + | + | yes | 0 | none | + | + |
Kreitschmann-Andermahr et al. [35] | Retrospective cohort | + | + | yes | 10 | TRH-LHRH test & ITT | + | + |
Aimaretti et al. [32] | Prospective cohort | - | - | yes | 0 | GHRH-arg | + | + |
Kreitschmann- Andermahr et al. [36] | Case series | + | + | yes | 8 | ITT (14 out of 45 pts) | + | + |
Jovanovic et al. [34] | Case series | + | + | yes | 0 | none | + | + |
Tanriverdi et al. [39] | Prosective cohort | + | + | no | 0 | GHRH-arg & glucagon test | + | + |
Klose et al. [40] | Prospective cohort | + | + | no | 0 | ITT (GHRH-arg if contraindicated) | + | + |
Lammert et al. [38] | Prospective cohort | + | + | yes | 4 | ACTH stimulation test (ITT in some patients) | + | + |
Dutta et al. [46] | Retrospective cohort | + | + | yes | 0 | none | + | + |
Gardner et al. [41] | Prospective cohort | + | + | no | 0 | GHRH-arg and glucagon test | + | + |
Khursheed et al. [43] | Prospective cohort | + | + | no | 0 | none | + | + |
Kronvall et al. [44] | Prospective cohort | + | + | no | 6 | GHRH-arg | no | no |
Karaca et al. [45] | Prospective cohort | + | + | no | 2 | Glucagon test | + | + |
Blijdorp et al. [42] | Prospective cohort | + | + | yes | 0 | Ghrelin test and GHRH-arg, Synacten test in some patients | + | + |