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Table 2 Summary of studies assessing frequency of pituitary deficiency after SAH

From: Hypopituitarism after subarachnoid haemorrhage, do we know enough?

Study

Time after SAH (months)

Patients n

GH%

ACTH%

TSH%

LH/FSH%

Testosterone%

Multiple%

Total%

Aimaretti et al. [37]

3

40

25

2.5

7.5

12.5

*

10

37.5

Brandt et al. [33]

12

10

10

0

20

10

30

30

30

Dimopoulou et al. [17]

12-24

30

37

10**

7***

13

*

13

47

Kreitschmann-Andermahr et al. [35]

12-66

40

20

40

4

0

0

12

55

Aimaretti et al. [32]

12

32

21.8

6.25

9

3

3

6

37.5

Kreitschmann-Andermahr et al. [36]

3-24

45

8

13

0

0

0

9

13

Jovanovic et al. [34]

12-120

93

29

22

2.5

7.5

*

7.5

49.5

Lammert et al. [38]

6

26

0

0

4

0

0

0

4

Tanriverdi et al. [39]

12

22

36

14

0

0

0

4

50

Klose et al. [40]

12-24

62

0

0

0

0

0

0

0

Gardner et al. [41]

12

50

10

2

0

0

0

0

12

Dutta et al. [47]

6

60

15

2

13

13

23

6

31.6

Kronvall et al. [44]

3-6

45

7

18

2

4

*

NR

27

Khursheed et al. [43]

9

73

NR

NR

3

0

0

0

3

Karaca et al. [45]

36

20

20

0

0

0

0

0

20

Blijdorp et al. [42]

6

43

14

0

0

28

*

7

30

  1. Abbreviations: n: numbers; %: percentage; FSH: follicle-stimulating hormone; LH: luteinizing hormone; TSH: thyroid-stimulating hormone; GH: growth hormone; ACTH: adrenocorticotropic hormone; NR: not reported; *Reporting LH, FSH and testosterone together as gonadotropin deficient; **ACTH hypo-responsive; ***Subclinical TSH deficient.