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Table 2 Summary of studies assessing frequency of pituitary deficiency after SAH

From: Hypopituitarism after subarachnoid haemorrhage, do we know enough?

Study Time after SAH (months) Patients n GH% ACTH% TSH% LH/FSH% Testosterone% Multiple% Total%
Aimaretti et al. [37] 3 40 25 2.5 7.5 12.5 * 10 37.5
Brandt et al. [33] 12 10 10 0 20 10 30 30 30
Dimopoulou et al. [17] 12-24 30 37 10** 7*** 13 * 13 47
Kreitschmann-Andermahr et al. [35] 12-66 40 20 40 4 0 0 12 55
Aimaretti et al. [32] 12 32 21.8 6.25 9 3 3 6 37.5
Kreitschmann-Andermahr et al. [36] 3-24 45 8 13 0 0 0 9 13
Jovanovic et al. [34] 12-120 93 29 22 2.5 7.5 * 7.5 49.5
Lammert et al. [38] 6 26 0 0 4 0 0 0 4
Tanriverdi et al. [39] 12 22 36 14 0 0 0 4 50
Klose et al. [40] 12-24 62 0 0 0 0 0 0 0
Gardner et al. [41] 12 50 10 2 0 0 0 0 12
Dutta et al. [47] 6 60 15 2 13 13 23 6 31.6
Kronvall et al. [44] 3-6 45 7 18 2 4 * NR 27
Khursheed et al. [43] 9 73 NR NR 3 0 0 0 3
Karaca et al. [45] 36 20 20 0 0 0 0 0 20
Blijdorp et al. [42] 6 43 14 0 0 28 * 7 30
  1. Abbreviations: n: numbers; %: percentage; FSH: follicle-stimulating hormone; LH: luteinizing hormone; TSH: thyroid-stimulating hormone; GH: growth hormone; ACTH: adrenocorticotropic hormone; NR: not reported; *Reporting LH, FSH and testosterone together as gonadotropin deficient; **ACTH hypo-responsive; ***Subclinical TSH deficient.