Figure 1From: POEMS syndrome, calciphylaxis and focal segmental glomerulosclerosis - VEGF as a possible link Calciphylaxis-induced skin changes on the right lower leg. Calciphylaxis-induced skin changes presented initially as a violaceous plaque-like lesion and a small ulcer (A) and progressed within two weeks to a deep necrotic ulcer with eschar (B).Back to article page