Web-based tool for dynamic functional outcome after acute ischemic stroke and comparison with existing models

BMC Neurology

Table 3 Sensitivity analysis of the DFS-AIS in the overall cohort (n = 12,026)

	Discharge mRS ≤ 2		3-month mRS ≤ 2		6-month mRS ≤ 2		1-year mRS ≤ 2
	AUROC	95% C.I.	AUROC	95% C.I.	AUROC	95% C.I.	AUROC	95% C.I.
Age
≤59	0.845	0.829-0.861	0.826	0.808-0.844	0.820	0.801-0.839	0.813	0.793-0.833
≥60	0.830	0.820-0.839	0.836	0.826-0.846	0.830	0.820-0.840	0.827	0.817-0.837
Gender
Male	0.834	0.823-0.845	0.832	0.821-0.843	0.834	0.823-0.845	0.834	0.823-0.845
Female	0.843	0.830-0.856	0.849	0.837-0.861	0.846	0.834-0.858	0.845	0.833-0.857
Time from onset to arrival (hours)
≤3	0.829	0.808-0.850	0.846	0.825-0.867	0.847	0.826-0.868	0.857	0.837-0.877
3-6	0.838	0.808-0.868	0.826	0.796-0.856	0.836	0.807-0.865	0.834	0.805-0.863
6-24	0.834	0.818-0.850	0.845	0.830-0.860	0.842	0.827-0.857	0.848	0.833-0.862
≥24	0.845	0.833-0.856	0.841	0.829-0.853	0.839	0.828-0.850	0.831	0.819-0.842
OCSP subtype
Lacunar infarction (LACI)	0.809	0.785-0.833	0.819	0.796-0.842	0.829	0.807-0.851	0.816	0.794-0.838
Partial anterior circulation infarct (PACI)	0.827	0.816-0.838	0.821	0.810-0.832	0.822	0.811-0.833	0.826	0.815-0.837
Total anterior circulation infarct (TACI)	0.855	0.830-0.880	0.917	0.900-0.936	0.912	0.892-0.932	0.905	0.885-0.925
Posterior circulation infarct (POCI)	0.853	0.833-0.873	0.846	0.826-0.866	0.840	0.820-0.860	0.845	0.826-0.846
Intravenous or intra-arterial thrombolysis	0.773	0.724-0.822	0.785	0.735-0.833	0.779	0.733-0.825	0.781	0.730-0.832

Abbreviation: mRS Modified Rankin Scale, AUROC Area Under the Receiver Operating Characteristic Curve, C.I. Confidence Interval, OCSP Oxfordshire Community Stroke Project.

ISSN: 1471-2377