NAb- (n = 136) | NAb + (n = 39) | p | |
---|---|---|---|
Female sex | 95 (69.9%) | 35 (89.7%) | 0.012 |
Mean age at MS diagnosis (years +/- SEM) | 33.8 +/- 0.9 | 35.2 +/- 1.5 | 0.48 |
Mean age at treatment initiation (years +/- SEM) | 35.5 +/- 0.9 | 37.3 +/- 1.6 | 0.32 |
Mean duration of MS course (years +/- SEM) | 5.3 +/- 0.5 | 4.9 +/- 0.9 | 0.66 |
Mean EDSS at inclusion consultation (+/- SEM) | 1.7 +/- 0.1 | 1.8 +/- 0.2 | 0.66 |
Mean ΔEDSS* (+/- SEM) | +0.1 +/- 0.1 | +0.4 +/- 0.1 | 0.035 |
Mean number of relapse before inclusion consultation (+/- SEM) | 2.4 +/- 0.1 | 2.4 +/- 0.2 | 0.98 |
Mean number of relapse between inclusion and follow-up consultations (+/- SEM) | 0.6 +/- 0.1 | 1.0 +/- 0.2 | 0.016 |
Number of non-responder patients | 69 (50.7%) | 27 (69.2%) | 0.041 |
Mean MFIS score (+/- SEM) | 34.2 +/- 1.7 | 47.3 +/- 2.9 | 0.0002 |
Number of fatigue patients | 69 (50.7%) | 31 (79.5%) | 0.0014 |
Mean MADRS score (+/- SEM) | 3.6 +/- 0.4 | 4.8 +/- 0.7 | 0.14 |
Mean MSTCQ score (+/- SEM) | 7.2 +/- 0.4 | 5.9 +/- 0.8 | 0.086 |
IFNβ type: | |||
- Intramuscular IFNβ-1a | 25 (18.5%) | 3 (7.9%) | 0.21 |
- Subcutaneous IFNβ-1a | 77 (57%) | 22 (57.9%) | |
- Subcutaneous IFNβ-1b | 33 (24.4%) | 13 (34.2%) |