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Table 3 Diagnosis of NMOSD using different MRI criteria

From: Comparison between the cranial magnetic resonance imaging features of neuromyelitis optica spectrum disorder versus multiple sclerosis in Taiwanese patients

  Sensitivity Specificity Positive predictive value Negative predictive value
1. Linear ependymal lesions 24% (6/25) 100% (29/29) 100% 60%
2. Unmet Matthews criteria* 40% (10/25) 79% (23/29) 63% 61%
3. 1 and 2 56% (14/25) 100% (29/29) 100% 73%
  1. *The Matthews criteria used to separate MS from NMOSD: at least 1 lesion adjacent to the body of the lateral ventricle and in the inferior temporal lobe; or the presence of a subcortical U-fiber lesion or a Dawson’s finger-type lesion.
  2. NMOSD: neuromyelitis optica spectrum disorder.