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Table 3 Biochemical values of patients with or without SCA in NMOSD

From: Comparison of clinical characteristics between neuromyelitis optica spectrum disorders with and without spinal cord atrophy

  

NMOSD with SCA (n = 23)

NMOSD without SCA (n = 162)

P

CSF Index

WBCs (106)

7 (2–20)

4 (0–70)

0.807

 

Protein (0.15-0.4 mg/ml)

0.23 (0.12-0.68)

0.24 (0.06-0.95)

0.395

 

Glucose (2.5-3.9 mg/ml)

3.5 (2.52-6.64)

3.28 (1.81-6.64)

0.151

 

Chloride (121.0-129.0 mg/ml)

127.6 (100.9-131.6)

126.95 (100.9-138.5)

0.134

 

OCB (+), n (%)

0/10 (0%)

11/75 (14.7%)

0.174

Serums Index

CRP (0–6 mg/l)

2.45 (0–62.5)

0.9 (0–20.5)

0.001**

 

ESR (0–20 mm/H)

19 (6–91)

12 (1–91)

0.045*

 

NMO-IgG (+), n (%)

16/23 (69.6%)

44/58 (75.9%)

0.155

 

ANA (+), n (%)

7/13 (53.8%)

40/91 (44%)

0.503

 

SSA (+), n (%)

2/15 (13.3%)

16/89 (18%)

0.660

 

SSB (+), n (%)

2/15 (13.3%)

8/89 (9%)

0.597

 

RF (+), n (%)

5/14 (30.8%)

7/51 (13.7%)

0.146

 

IgG (8–16 g/L)

12.58 (7.56-30.36)

11.9 (1.33-33.22)

0.483

 

IgA (0.7-3.3 g/L)

1.56 (0.19-4.59)

1.57 (0.7-4.34)

0.894

 

IgM (0.5-2.2 g/L)

1.03 (0.05-1.96)

1.19 (0.45-6.54)

0.128

 

C3 (0.8-1.6 g/l)

0.99 (0.13-1.66)

1.06 (0.51-2.11)

0.529

 

C4 (0.1-0.4 g/l)

0.22 (0.11-0.32)

0.2 (0.04-1.27)

0.719

 

CH50 (23–46 U/ml )

37 (16–71)

47 (10–65)

0.103

  1. NMOSD = neuromyelitis optica spectrum disorders; SCA = spinal cord atrophy; CSF = cerebrospinal fluid; OCB = oligoclonal banding; CRP = C-reactive protein; ESR = erythrocyte sedimentation rate; NMO-IgG = anti-AQP4IgG autoantibodies; ANA = antinuclear antibodies; SSA = anti-SSA/Ro antibodies; SSB = anti-SSB/La antibodies; RF = rheumatoid factor; *P < 0.05; **P < 0.01.