Table 2 Adjusted* binomial logistic regression full model in the matched cohort for (1) good outcome, (2) mortality, (3) sICH, and (4) fatal ICH
From: Impact of sex in stroke thrombolysis: a coarsened exact matching study
Good Outcome | Mortality | sICH | Fatal ICH | |||||
|---|---|---|---|---|---|---|---|---|
OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | |
Sex | 1.04 (0.76–1.43) | 0.774 | 1.13 (0.73–1.73) | 0.572 | 3.62 (1.77–7.41) | <0.001 | 4.53 (1.61–12.7) | 0.004 |
sICH | 0.14 (0.03–0.51) | 0.002 | 20.6 (9.52–44.7) | <0.001 | ||||
NIHSS | 0.94 (0.92–0.97) | <0.001 | 1.10 (1.07–1.13) | <0.001 | 1.02 (0.98–1.07) | ns | 1.03 (0.96–1.09) | ns |
Age | 0.95 (0.93–0.97) | <0.001 | 1.09 (1.06–1.12) | <0.001 | 0.97 (0.94–1.01) | ns | 1.01 (0.95–1.06) | ns |
TTT [min] | 0.99 (0.99–0.99) | 0.003 | 0.99 (0.99–0.99) | 0.003 | 1.00 (1.00–1.00) | ns | 1.00 (1.00–1.00) | ns |
Diastolic BP [mmHg] | 0.98 (0.97–0.99) | 0.007 | 1.00 (0.99–1.02) | ns | 0.99 (0.97–1.02) | ns | 1.00 (0.97–1.03) | ns |
Current Smoker | 0.49 (0.26–0.95) | 0.035 | 1.26 (0.37–4.20) | ns | 0.07 (0.00–5.07) | ns | 0.21 (0.00–15.2) | ns |
Glucose [mg/dl] | 0.99 (0.99–1.00) | ns | 1.00 (1.00–1.01) | 0.009 | 1.00 (0.99–1.01) | ns | 1.00 (0.99–1.01) | ns |
Hyperlipidemia | 0.79 (0.49–1.27) | ns | 1.99 (1.10–3.61) | 0.022 | 1.21 (0.52–2.82) | ns | 0.85 (0.24–3.07) | ns |
Hypertension | 1.21 (0.75–1.96) | ns | 0.44 (0.21–0.90) | 0.026 | 3.03 (0.64–14.3) | ns | 0.49 (0.12–2.05) | ns |
Antithrombotics | 0.76 (0.52–1.11) | ns | 1.29 (0.81–2.05) | ns | 2.13 (1.04–4.37) | 0.040 | 3.76 (1.26–11.2) | 0.018 |
Atrial fibrillation | 0.84 (0.58–1.21) | ns | 1.10 (0.70–1.71) | ns | 1.04 (0.53–2.01) | ns | 1.48 (0.60–3.62) | ns |
CHD | 0.69 (0.39–1.21) | ns | 1.73 (0.98–3.05) | 0.055 | 0.91 (0.37–2.22) | ns | 1.39 (0.46–4.16) | ns |
Diabetes | 0.99 (0.62–1.57) | ns | 0.77 (0.44–1.37) | ns | 2.01 (0.95–4.26) | 0.070 | 1.32 (0.44–3.91) | ns |
Previous Stroke | 0.83 (0.49–1.39) | ns | 1.35 (0.77–2.37) | ns | 1.91 (0.89–4.10) | 0.097 | 2.02 (0.73–5.62) | ns |
OAC | 1.58 (0.76–3.28) | ns | 1.63 (0.68–3.90) | ns | 0.11 (0.00–7.58) | ns | 0.26 (0.00–20.2) | ns |
Platelet [count/nl] | 0.99 (0.99–1.00) | ns | 1.00 (0.99–1.00) | ns | 1.00 (0.99–1.00) | ns | 1.00 (0.99–1.00) | ns |
Hemisphere, left | 0.83 (0.60–1.14) | ns | 1.19 (0.76–1.84) | ns | 0.62 (0.34–1.14) | ns | 0.66 (0.29–1.52) | ns |
Statin | 0.95 (0.55–1.63) | ns | 0.74 (0.37–1.49) | ns | 0.61 (0.22–1.71) | ns | 0.80 (0.15–4.10) | ns |