Thinner changes of the retinal nerve fiber layer in patients with mild cognitive impairment and Alzheimer’s disease

Table 2 RNFL thickness (μm) in patients with MCI, mild, moderate, severe AD and control subjects (mea ± SD)

	MCI	mild AD	moderate AD	severe AD	control F value
S	115.14 ± 13.51^▲	111.78 ± 11.67^▲	108.89 ± 12.42^▲■	101.56 ± 19.32^▲■	119.10 ± 15.34
S	115.14 ± 13.51^▲	111.78 ± 11.67^▲	108.89 ± 12.42^▲■	101.56 ± 19.32^▲■	2.012*
I	120.23 ± 18.04	115.11 ± 10.56	113.23 ± 16.21	111.41 ± 10.64^▲■	125.67 ± 11.23
I	120.23 ± 18.04	115.11 ± 10.56	113.23 ± 16.21	111.41 ± 10.64^▲■	5.549**
N	74.80 ± 12.36	69.76 ± 11.64	64.41 ± 15.87	61.12 ± 17.54	79.98 ± 12.87
N	74.80 ± 12.36	69.76 ± 11.64	64.41 ± 15.87	61.12 ± 17.54	1.035
T	63.78 ± 13.16	61.17 ± 12.14	60.43 ± 11.87	60.41 ± 10.82	67.34 ± 15.27
T	63.78 ± 13.16	61.17 ± 12.14	60.43 ± 11.87	60.41 ± 10.82	1.256
M	95.37 ± 17.11^▲	91.61 ± 10.10^▲	91.68 ± 12.37^▲■	87.13 ± 17.05^▲▲■	100.12 ± 15.01
M	95.37 ± 17.11^▲	91.61 ± 10.10^▲	91.68 ± 12.37^▲■	87.13 ± 17.05^▲▲■	7.985**

S: superior of Peripapillary RNFL thickness; I: inferior of Peripapillary RNFL thickness; N: nasal of Peripapillary RNFL thickness; T: temporal of Peripapillary RNFL thickness; M: total mean of RNFL thickness; Compared with the control group:^▲P < 0.05,^▲▲P < 0.01; comparison to MCI:^■P < 0.05 F test: *p < 0.05, **p < 0.001.

ISSN: 1471-2377