Skip to main content

Table 3 Comparison of neuropsychological assessment

From: Validation of NINDS-CSN neuropsychological battery for vascular cognitive impairment in Chinese stroke patients

Cognitive tests Controls Stroke patients P value b Cohen’s d
Executive/Activation     
ANT 17.2 ± 4.0 11.9 ± 4.1 <0.001 1.31
WAIS-III Digit symbol-coding 22.4 ± 7.9 3.4 ± 6.6 <0.001 1.24
TMT A time (sec) 45.7 ± 15.5 90.7 ± 59.1 0.001 1.04
TMT B time (sec) 108.2 ± 42.3 176.4 ± 97.4 0.009 0.92
Domain z score   −1.01   
Language     
Modified BNT 11.4 ± 2.2 8.8 ± 2.7 0.003 1.03
Domain z score   −0.92   
Visuospatial     
RCFT copy 34.6 ± 1.8 30.2 ± 6.9 0.002 0.88
Domain z score   −0.80   
Memory     
HVLT-R delayed recall 7.6 ± 2.6 4.5 ± 2.7 <0.001 1.16
RCFT delayed recall 18.6 ± 6.3 11.9 ± 8.8 <0.001 0.89
Domain z score   −0.93   
Neuropsychiatric/depressive symptoms     
NPI-Qa 2 (0–11) 4 (0–29.5) 0.008 0.41
GDSa 2 (1–3) 3 (1–7.25) 0.024 0.63
Supplemental tests     
MMSE 28.6 ± 1.1 26.3 ± 3.2 <0.001 0.94
MoCA-BJ 23.8 ± 2.9 17.9 ± 4.4 <0.001 1.59
Protocol summary scores     
60-min 0.46 ± 0.45 −0.49 ± 0.72 <0.001 1.57
30-min 0.53 ± 0.67 −0.53 ± 0.65 <0.001 1.60
5-min 0.41 ± 0.47 −0.42 ± 0.71 <0.001 1.38
  1. aData shown in median (Interquartile range); bModel controlled for years of education.
  2. Abbreviations: ANT Animal naming test, TMT Trail making test, BNT Boston naming test, RCFT Rey-Osterrieth Complex Figure Test, HVLT-R Revised Hopkins verbal learning test, NPI-Q Neuropsychiatric Inventory questionnaire, GDS Geriatric Depression Scale, MMSE Mini-Mental State Examination, MoCA-BJ Montreal Cognitive Assessment-Beijing version.