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Table 2 Changes in gait measurements following a physical rehabilitation program

From: A personalized, intense physical rehabilitation program improves walking in people with multiple sclerosis presenting with different levels of disability: a retrospective cohort

Variable

Mean (S.E)

Pre

Post

Mean difference (95% CI)

P- Value

Pre-post change (%)

Entire group (EDSS range 2–6.5) (n = 312)

10mWT (s)

15.4 (0.7)

13.0 (0.6)

−2.3 (−1.4, −3.3)

<0.001*

−10.1 (1.7)

20mWT (s)

33.8 (1.7)

29.0 (1.6)

−4.8 (−2.7, −6.9)

<0.001*

−10.6 (1.7)

2mWT (m)

120.8 (3.1)

136.1 (3.8)

15.3 (11.2, 19.5)

<0.001*

14.9 (1.9)

TUG (s)

15.8 (0.8)

14.2 (0.6)

−1.6 (−0.7, −2.6)

0.001*

−5.4 (1.6)

Mild disability (EDSS range <4.5) (n = 87)

10mWT (s)

9.5 (0.5)

8.4 (0.4)

−1.1 (−1.7, −0.6)

<0.001*

−9.2 (2.3)

20mWT (s)

20.1 (1.0)

17.9 (0.8)

−2.1 (−0.9, −3.4)

0.001*

−7.7 (2.3)

2mWT (m)

143.2 (4.3)

158.1 (5.6)

14.9 (8.7, 21.1)

0.001*

10.9 (2.3)

TUG (s)

9.8 (0.5)

8.9 (0.3)

−0.9 (−1.5, −0.3)

0.006*

−5.1 (2.4)

Moderate disability (EDSS = 4.5-5.5) (n = 104)

10mWT (s)

11.5 (0.5)

9.9 (0.4)

−1.6 (−1.0, −2.2)

<0.001*

−10.3 (2.1)

20mWT (s)

24.5 (1.0)

21.2 (1.1)

−3.4 (−2.1, −4.7)

<0.001*

−11.3 (1.9)

2mWT (m)

120.3 (4.2)

140.6 (5.2)

20.3 (13.1, 27.5)

<0.001*

19.0 (3.4)

TUG (s)

12.3 (1.1)

10.8 (0.4)

−1.5 (−0.6, 3.5)

0.156

−3.9 (2.3)

Severe disability (EDSS 6.0-6.5) (n = 121)

10mWT (s)

23.2 (1.5)

19.2 (1.4)

−4.0 (−6.4, −1.6)

0.001*

−10.5 (3.9)

20mWT (s)

52.3 (3.6)

43.1 (3.7)

−9.2 (−14.1, −4.2)

<0.001*

−12.1 (3.7)

2mWT (m)

94.5 (7.4)

113.1 (11.2)

18.6 (6.7, 30.6)

0.004*

16.2 (5.4)

TUG (s)

23.8 (1.6)

21.4 (1.4)

−2.4 (−4.2, −0.6)

0.011*

−6.8 (3.1)

  1. EDSS- expanded disability status scale; 10mWT- ten-meter walking test; 20mWT- twenty-meter walking test; 2mWT- two-minute walking test; TUG - timed up and go test. *P<0.05.