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Table 2 Changes in gait measurements following a physical rehabilitation program

From: A personalized, intense physical rehabilitation program improves walking in people with multiple sclerosis presenting with different levels of disability: a retrospective cohort

Variable Mean (S.E)
Pre Post Mean difference (95% CI) P- Value Pre-post change (%)
Entire group (EDSS range 2–6.5) (n = 312)
10mWT (s) 15.4 (0.7) 13.0 (0.6) −2.3 (−1.4, −3.3) <0.001* −10.1 (1.7)
20mWT (s) 33.8 (1.7) 29.0 (1.6) −4.8 (−2.7, −6.9) <0.001* −10.6 (1.7)
2mWT (m) 120.8 (3.1) 136.1 (3.8) 15.3 (11.2, 19.5) <0.001* 14.9 (1.9)
TUG (s) 15.8 (0.8) 14.2 (0.6) −1.6 (−0.7, −2.6) 0.001* −5.4 (1.6)
Mild disability (EDSS range <4.5) (n = 87)
10mWT (s) 9.5 (0.5) 8.4 (0.4) −1.1 (−1.7, −0.6) <0.001* −9.2 (2.3)
20mWT (s) 20.1 (1.0) 17.9 (0.8) −2.1 (−0.9, −3.4) 0.001* −7.7 (2.3)
2mWT (m) 143.2 (4.3) 158.1 (5.6) 14.9 (8.7, 21.1) 0.001* 10.9 (2.3)
TUG (s) 9.8 (0.5) 8.9 (0.3) −0.9 (−1.5, −0.3) 0.006* −5.1 (2.4)
Moderate disability (EDSS = 4.5-5.5) (n = 104)
10mWT (s) 11.5 (0.5) 9.9 (0.4) −1.6 (−1.0, −2.2) <0.001* −10.3 (2.1)
20mWT (s) 24.5 (1.0) 21.2 (1.1) −3.4 (−2.1, −4.7) <0.001* −11.3 (1.9)
2mWT (m) 120.3 (4.2) 140.6 (5.2) 20.3 (13.1, 27.5) <0.001* 19.0 (3.4)
TUG (s) 12.3 (1.1) 10.8 (0.4) −1.5 (−0.6, 3.5) 0.156 −3.9 (2.3)
Severe disability (EDSS 6.0-6.5) (n = 121)
10mWT (s) 23.2 (1.5) 19.2 (1.4) −4.0 (−6.4, −1.6) 0.001* −10.5 (3.9)
20mWT (s) 52.3 (3.6) 43.1 (3.7) −9.2 (−14.1, −4.2) <0.001* −12.1 (3.7)
2mWT (m) 94.5 (7.4) 113.1 (11.2) 18.6 (6.7, 30.6) 0.004* 16.2 (5.4)
TUG (s) 23.8 (1.6) 21.4 (1.4) −2.4 (−4.2, −0.6) 0.011* −6.8 (3.1)
  1. EDSS- expanded disability status scale; 10mWT- ten-meter walking test; 20mWT- twenty-meter walking test; 2mWT- two-minute walking test; TUG - timed up and go test. *P<0.05.