Table 4 Sensitivity and specificity of sAxl in CSF and plasma to discriminate between RIA and UIA

0.02

100.00 (88.43 to 100.00)

13.33 (3.76 to 30.72)

1.15

0.00

0.09

90.00 (73.47 to 97.89)

66.67 (47.19 to 82.71)

2.70

0.15

0.10

86.67 (69.28 to 96.24)

70.00 (50.60 to 85.27)

2.89

0.19

0.11

76.67 (57.72 to 90.07)

83.33 (65.28 to 94.36)

4.60

0.28

0.12

73.33 (54.11 to 87.72)

90.00 (54.11 to 87.72)

7.33

0.30

0.14

63.33 (43.86 to 80.07)

93.33 (77.93 to 99.18)

9.50

0.39

Cut off (nM)

Sensitivity % (95% CI)

Specificity % (95% CI)

LR+

LR-

0.4

100 (83.16 to 100.0)

5 (0.1265 to 24.87)

1.05

0.00

0.5

90 (68.30 to 98.77)

15 (3.207 to 37.89)

1.06

0.67

1

80 (56.34 to 94.27)

45 (23.06 to 68.47)

1.45

0.44

1.2

65 (40.78 to 84.61)

65 (40.78 to 84.61)

1.86

0.54

1.7

50 (27.20 to 72.80)

80 (56.34 to 94.27)

2.50

0.63