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Table 2 Demographic and clinical details at baseline and at six months for cognitively impaired and non-cognitively impaired stroke survivors

From: Cognitive impairment six months after ischaemic stroke: a profile from the ASPIRE-S study

 

Cognitive impairment

No cognitive impairment

 
 

(n = 128; MoCA < = 25)

(n = 98; MocA >26)

 
 

N (%)

N (%)

P value

Univariate OR

95% CI

Age (Mean, ± SD)

71.8 (11.4)

63.2 (13.1)

0.001

1.06

1.02-1.09

Sex

     

Female

63 (67.7)

30 (32.3)

<0.001

2.19

1.97- 2.45

Health Insurance status as proxy SES

     

Public patient

102 (65.8)

53 (34.2)

   

Private patient

26 (36.6)

45 (63.4)

0.001

.33

.14-.63

Baseline risk factors

     

Previous TIA/Stroke

41 (74.5)

14 (25.5)

<0.001

2.83

1.6-4.9

Heart disease

42 (63.6)

24 (36.4)

0.91

1.5

.63-3.6

Hypertension

76 (60.3)

50 (39.7)

0.055

1.4

.99-1.98

Diabetes

24 (64.9)

13 (35.1)

0.059

1.5

.98-2.31

Hypercholesterolemia

65 (58.6)

46 (41.4)

0.23

1.16

.91-1.49

Smoker

34 (52.3)

31 (47.7)

0.18

.78

.54-1.12

Atrial fibrillation

53 (63.9)

30 (36.1)

<0.001

1.6

1.26-1.04

Carotid stenosis

21 (61.8)

13 (38.9)

<0.001

1.28

1.14-1.45

Bamford classification

     

TACS

6 (66.7)

3 (33.3)

0.67

1.56

.21-11.63

PACS

51 (55.4)

41 (44.6)

0.7

.92

.1-1.4

POCS

36 (53.7)

31 (46.3)

<0.001

.84

.77-.92

LACS

33 (62.2)

20 (37.8)

0.002

1.35

1.12-1.64

TOAST classification

     

Large artery atherosclerosis

19 (52.8)

17 (47.2)

0.54

.83

.46-1.49

Cardioembolism

52 (59.8)

35 (40.2)

0.22

1.23

.88-1.72

Small vessel occlusion

12 (42.9)

16 (57.1)

<0.001

.53

.45-.63

Other determined aetiology

4 (30.8)

9 (68.2)

<0.001

.31

.23-.45

Undetermined aetiology

41 (66.1)

21 (33.9)

0.3

1.72

.61-4.89

Stroke severity (SSS scale; Median, IQR)

51 (42–57.5)

56 (49–58)

<0.001

.92

.89-.94

Functional dependency

     

Pre-stroke function (mRS; Median, IQR)

0 (0–0)

0 (0–0)

0.02

2.07

1.08-3.95

Function at 72 hours (mRS; Median, IQR)

3 (1–4)

1 (0–3)

<0.001

1.56

1.41-1.71

Function at six months

2 (1–3)

1 (1–2)

<0.001

1.76

1.32-2.34

(mRS; Median, IQR)

VES (> = 3)

71 (73.2)

26 (26.8)

0.01

5.8

1.51-22.53

(n = 200)

HADS-D (>7)

24 (66.7)

12 (33.7)

0.16

2

.76-5.26

(n = 190)

HADS-A (>7)

27 (50.9)

26 (49.1)

.98

0.95

.64-1.52

(n = 190)

SSQoL (Median, IQR)

135 (110–153)

152 (135–170)

<0.001

0.97

.96-.98

(n = 173)

  1. OR, odds ratio; CI, confidence interval; SD, standard deviation; SES, socioeconomic status; TIA, transient ischaemic attack; TACS, total anterior circulation stroke; PACS, partial anterior circulation stroke; POCS, posterior circulation stroke; LACS, lacunar stroke; SSS, stroke severity; mRS, modified Rankin Scale; VES, Vulnerable Elders Survey; HADS-D, Hospital Anxiety and Depression Scale- Depression; HADS-A, Hospital Anxiety and Depression Scale- Anxiety; SSQoL, Stroke Specific Quality of Life.
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BMC Neurology

ISSN: 1471-2377

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