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Table 2 The clinical manifestations of TPP patients with KCNJ18 gene mutations

From: The clinical and genetic features in a cohort of mainland Chinese patients with thyrotoxic periodic paralysis

Case

Gender / age

Attack duration

Symptoms of weakness

Hyperthyroidism

Potassium mmol / L

CK IU / L

TSH uIU / ml

FT3 pg / ml

FT4 ng / dl

KCNJ18 mutation

1

Male/19

2 h

Quadriplegia

Weight loss, goiter

1.9

2093

<0.03

8.2

3.5

p.Q126X

2

Male/20

6 h

Quadriplegia

Weight loss

2.4

1476

<0.03

12.3

5.8

p.A200P

3

Male/23

3 h

Quadriplegia

Tremor

2.1

1205

<0.03

7.6

5.1

p.K360T

4

Male/25

8 h

Quadriplegia

Weight loss

1.6

2310

<0.03

16.8

9.3

p. E388K

  1. Abbreviation: CK creatine kinase, TSH Thyroid Stimulating Hormone, FT3 free triiodothyronine, FT4 free thyroxine.