Table 3 Analysis of clinical variables in TPP patients between with KCNJ18 mutation and without KCNJ18 mutation
Variables | With KCNJ18 mutations (n = 4) | Without KCNJ18 mutations (n = 123) | P value |
|---|---|---|---|
Age | 21.75 ± 2.75 | 25.23 ± 16.67 | 0.487 |
Sex (m/f) | 4/0 (100%/0) | 123/0 (100%/0) | - |
Weakness duration (h) | 4.8 ± 2.8 | 27.6 ± 11.6 | 0.006 |
Soreness or numbness | 3 (75.0%) | 21 (17.1%) | 0.021 |
Quadriplegia | 4 (100%) | 66 (53.7%) | 0.127 |
HyperCKmia | 4 (100%) | 75 (61.0%) | 0.296 |
Hyperthyroidism symptoms | |||
Tremor | 2 (50.0%) | 47 (38.2%) | 0.639 |
Weight loss | 3 (75.0%) | 30 (24.4%) | 0.054 |
Goiter | 1 (25.0%) | 12 (9.8%) | 0.354 |
Weakness recurrence | 3 (75.0%) | 26 (21.1%) | 0.046 |