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Table 3 Analysis of clinical variables in TPP patients between with KCNJ18 mutation and without KCNJ18 mutation

From: The clinical and genetic features in a cohort of mainland Chinese patients with thyrotoxic periodic paralysis

Variables With KCNJ18 mutations (n = 4) Without KCNJ18 mutations (n = 123) P value
Age 21.75 ± 2.75 25.23 ± 16.67 0.487
Sex (m/f) 4/0 (100%/0) 123/0 (100%/0) -
Weakness duration (h) 4.8 ± 2.8 27.6 ± 11.6 0.006
Soreness or numbness 3 (75.0%) 21 (17.1%) 0.021
Quadriplegia 4 (100%) 66 (53.7%) 0.127
HyperCKmia 4 (100%) 75 (61.0%) 0.296
Hyperthyroidism symptoms
Tremor 2 (50.0%) 47 (38.2%) 0.639
Weight loss 3 (75.0%) 30 (24.4%) 0.054
Goiter 1 (25.0%) 12 (9.8%) 0.354
Weakness recurrence 3 (75.0%) 26 (21.1%) 0.046