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Table 1 Schedule of assessments

From: Cohort study ON Neuroimaging, Etiology and Cognitive consequences of Transient neurological attacks (CONNECT): study rationale and protocol

Assessment Baseline Follow-up
Demographics   
Age, sex X  
Education X  
Working status X  
Marital status X  
Structured assessment of TIA/TNA presentation   
Duration of symptoms X  
Number of episodes in week before inclusion X  
Focal symptoms* X  
Nonfocal symptoms* X  
Incident focal symptoms*   X
Incident nonfocal symptoms*   X
Medical history   
Hypertension X X
Dyslipidemia X X
Diabetes mellitus X X
Atrial fibrillation X X
Other cardiovascular diseases X  
First-degree relatives with cardiovascular disease X  
Smoking status X X
Alcohol consumption X X
Drug abuse X X
Hypercoagulability X  
Acute infection X  
Migraine X  
Previous TIA/TNA X  
Carotid endarterectomy X X
Epilepsy X X
Depression X X
Current medication use X X
Incident cardiovascular events   X
Incident TIA, cerebral infarction or hemorrhage   X
Physical examination   
Length and weight, BMI X  
Blood pressure X  
Neurological examination X  
ECG   
(Paroxysmal) atrial fibrillation X  
Ischemia X  
Left ventricular hypertrophy X  
Fasting laboratory investigations   
Glucose X  
Lipid profile X  
Creatinine X  
Neuropsychological assessment   
Global cognitive function   
Mini Mental State Examination X  
Frontal Assessment Battery X X
Episodic memory   
Rey Auditory Verbal Learning Test X X
Executive function   
Verbal fluency X X
Stroop Color Word Test (interference score) X X
Brixton Spatial Anticipation Test X X
Information processing speed   
Symbol-Digit Modalities Test X X
Stroop Color Word Test (Cards I and II) X X
Attention   
Verbal Series Attention Test X X
Subjective cognitive failures   
Cognitive failures Questionnaire X X
Depressive symptoms   
Hospital Anxiety and Depression Scale X X
Sleep disorders   
Scales for Outcomes in Parkinson’s Disease - Sleep X X
Fatigue   
Checklist on Individual Strength X X
Prior cognitive performance   
Informant Questionnaire on Cognitive Decline in the Elderly X X
MRI   
Anatomical sequences (T1, T2, FLAIR, T2*) X X
Diffusion-weighted imaging X  
MR angiography X  
Susceptibility-weighted imaging   X
Diffusion tensor imaging   X
Resting-state functional MRI   X
  1. Empty cells indicate no assessment. BMI indicates body-mass index; FLAIR, fluid-attenuated inversion recovery; TNA, transient neurological attack; ToF, time-of-flight.
  2. *Presence of 18 predefined symptoms, both focal and nonfocal (see also Table 2).
  3. Myocardial infarction, coronary artery bypass grafting, percutaneous transluminal coronary angioplasty, valvular heart disease and peripheral revascularization procedures.