Skip to main content

Table 3 Changes (%) in mean and maximum BOLD activities in 3 Brodmann areas (BA) during the motor task at session 1 (baseline), 2 (6 weeks), and 3 (12 weeks)

From: Cortical activation changes and improved motor function in stroke patients after focal spasticity therapy– an interventional study applying repeated fMRI

BA4a

 

BOLD mean

BOLD max

Pt #

L1/L2/L3

R1/R2/R3

(L-R)/R %

L1/L2/L3

R1/R2/R3

(L-R)/R %

1

2.90/2.02/1.86

3.19/0.96/0.95

−9/11/10

19.5/10.1/18.9

22.1/5.52/13.7

−12/84/37

2

2.31/3.52/3.68

2.86/5.58/3.80

−19/-36/-3

10.9/28.4/31.7

16.5/33.5/17.2

−34/-15/85

3

2.24/1.43/3.3

2.67/1.36/2.91

−16/5/13

17.8/10.9/19.7

19.1/8.20/15.0

−7/33/31

4

1.20/2.71/2.18

1.59/2.50/1.82

−25/8/20

8.79/26.8/15.4

13.8/14.9/11.9

−36/80/30

5

2.76/2.64/2.58

1.96/3.38/2.38

41/11/8

22.4/19.8/17.0

18.5/13.7/9.64

21/45/76

6

3.62/0.92/0.71

4.69/1.05/1.28

−23/-12/-45

33.1/3.52/4.35

32.0/7.04/15.1

4/-50/-71

Mean

2.51/2.21/2.39

2.83/2.29/2.19

−8/14/15

18.8/16.6/17.8

20.3/13.8/13.8

−11/29/31

Healthy subjects; mean

1.16/1.05

0.66/0.49*

79/130

10.6/8.0

5.70/3.66

108/160

p values

0.011/0.014

0.001/0.001

0.002/0.004

0.034/ns

0.001/0.001

0.003/0.001

BA4p

 

BOLD mean

BOLD max

Pt #

L1/L2/L3

R1/R2/R3

(L-R)/R %

L1/L2/L3

R1/R2/R3

(L-R)/R %

1

2.37/1.50/1.55

2.42/0.76/0.83

−2/98/87

19.5/10.1/18.9

22.1/4.53/13.7

−12/123/37

2

1.14/2.75/2.50

1.88/3.44/2.77

−39/-20/-10

8.11/28.4/31.7

12.1/22.8/17.2

−33/25/85

3

1.40/0.98/2.65

1.16/0.73/1.44

21/34/84

10.7/7.89/18.1

14.0/5.18/10.8

−24/52/67

4

0.99/1.41/1.26

1.39/1.31/1.30

−29/8/-3

8.79/16.2/6.91

13.8/14.0/11.9

−36/16/-42

5

2.27/2.12/1.45

1.59/1.70/2.18

43/24/-33

18.5/13.9/8.91

18.5/1.1/9.22

0/15/-3

6

2.96/0.86/0.61

2.96/0.70/0.67

0/22/-9

33.1/2.96/4.35

25.6/7.04/5.38

29/-58/-19

Mean

1.86/1.60/1.67

1.90/1.44/1.53

−1/28/19

16.4/13.3/14.8

17.7/10.9/11.4

−13/29/21

Healthy subjects; mean

0.94/0.87

0.51/0.37*

85/57

8.08/6.73

4.16/2.86

122/149

p values

0.045/0.020

0.001/0.001

0.003/0.004

0.045/ns

0.001/0.001

0.002/0.008

BA6

      
 

BOLD mean

BOLD max

Pt #

L1/L2/L3

R1/R2/R3

(L-R)/R %

L1/L2/L3

R1/R2/R3

(L-R)/R %

1

2.81/1.96/1.71

3.10/0.94/0.67

−9/108/155

36.4/13.0/18.7

34.7/13.0/3.56

5/0/430

2

2.59/3.93/3.89

2.64/6.15/4.11

−1/-36/-5

10.9/32.8/33.2

16.5/39.5/28.3

−34/-17/17

3

3.08/1.78/3.81

2.71/1.50/3.59

14/0/619

18.3/13.8/22.7

19.1/9.60/20.4

−4/44/11

4

1.51/1.26/2.62

1.30/2.28/1.98

16/-40/33

15.6/26.8/16.7

8.50/13.6/11.9

84/96/41

5

2.52/3.09/4.72

1.53/2.25/3.64

65/37/30

31.9/24.1/39.0

17.7/14.8/25.1

80/63/55

6

5.09/1.23/0.88

4.10/1.06/1.16

24/15/-24

27.0/13.9/5.99

32.0/10.3/15.1

−16/35/-60

Mean

2.93/2.21/2.94

2.56/2.37/2.52

18/16/32

23.3/20.7/22.7

21.4/16.8/17.4

19/37/82

Healthy subjects; mean

1.09/0.94

0.69/0.56

61/76

12.7/9.62

6.08/4.69

119/116

p values

0.003/0.004

0.001/0.001

0.015/0.034

0.034/0.011

0.003/0.001

0.020/0.015

  1. Values from the 10 healthy subjects studied twice serve as reference; p values refer to between-group differences. *p < 0.05 for session 1 vs. 2 in healthy subjects (p < 0.002 applying Bonferroni correction in bold font).