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Table 3 The distribution of polymorphisms in the case and control groups

From: DRD and GRIN2B polymorphisms and their association with the development of impulse control behaviour among Malaysian Parkinson’s disease patients

SNP Allele frequency Genotype frequency p -value
Wild type Heterozygote Mutant
DRD1 rs4532 Control C (0.06) T (0.94) CC (0.02) TC (0.07) TT (0.90) 0.26
Case C (0.24) T (0.76) CC (0.06) TC (0.37) TT (0.57)
DRD1 rs4867798 Control T (0.68) C (0.32) TT (0.42) TC (0.52) CC (0.06) 0.35
Case T (0.54) C (0.46) TT (0.36) TC (0.36) CC (0.28)
DRD1 rs265981 Control T (0.18) C (0.82) TT (0.03) TC (0.32) CC (0.66) 0.51
Case T (0.21) C (0.79) TT (0.02) TC (0.36) CC (0.66)
DRD2/ANKK1 rs1800497 Control C (0.48) T (0.52) TT (0.30) TC (0.44) CC (0.26) 0.27
Case C (0.71) T (0.29) TT (0.09) TC (0.40) CC (0.51)
DRD3 rs3732783 Control T (1.00) C (0.00) TT (1.00) TC (0.00) CC (0.00) 0.0014**
Case T (0.95) C (0.05) TT (0.94) TC (0.02) CC (0.04)
DRD3 rs6280 Control C (0.24) T (0.76) CC (0.05) TC (0.50) TT (0.57) 0.61
Case C (0.33) T (0.76) CC (0.08) TC (0.38) TT (0.42)
GRIN2B rs7301328 Control G (0.50) C (0.50) GG (0.57) CG (0.38) CC (0.05) 0.47
Case G (0.28) C (0.72) GG (0.42) CG (0.50) CC (0.08)
  1. Data were analysed using Fisher’s exact test. **,p < 0.01, which indicates a statistically significant difference.