Skip to main content

Table 3 The distribution of polymorphisms in the case and control groups

From: DRD and GRIN2B polymorphisms and their association with the development of impulse control behaviour among Malaysian Parkinson’s disease patients

SNP

Allele frequency

Genotype frequency

p -value

Wild type

Heterozygote

Mutant

DRD1 rs4532

Control

C (0.06)

T (0.94)

CC (0.02)

TC (0.07)

TT (0.90)

0.26

Case

C (0.24)

T (0.76)

CC (0.06)

TC (0.37)

TT (0.57)

DRD1 rs4867798

Control

T (0.68)

C (0.32)

TT (0.42)

TC (0.52)

CC (0.06)

0.35

Case

T (0.54)

C (0.46)

TT (0.36)

TC (0.36)

CC (0.28)

DRD1 rs265981

Control

T (0.18)

C (0.82)

TT (0.03)

TC (0.32)

CC (0.66)

0.51

Case

T (0.21)

C (0.79)

TT (0.02)

TC (0.36)

CC (0.66)

DRD2/ANKK1 rs1800497

Control

C (0.48)

T (0.52)

TT (0.30)

TC (0.44)

CC (0.26)

0.27

Case

C (0.71)

T (0.29)

TT (0.09)

TC (0.40)

CC (0.51)

DRD3 rs3732783

Control

T (1.00)

C (0.00)

TT (1.00)

TC (0.00)

CC (0.00)

0.0014**

Case

T (0.95)

C (0.05)

TT (0.94)

TC (0.02)

CC (0.04)

DRD3 rs6280

Control

C (0.24)

T (0.76)

CC (0.05)

TC (0.50)

TT (0.57)

0.61

Case

C (0.33)

T (0.76)

CC (0.08)

TC (0.38)

TT (0.42)

GRIN2B rs7301328

Control

G (0.50)

C (0.50)

GG (0.57)

CG (0.38)

CC (0.05)

0.47

Case

G (0.28)

C (0.72)

GG (0.42)

CG (0.50)

CC (0.08)

  1. Data were analysed using Fisher’s exact test. **,p < 0.01, which indicates a statistically significant difference.