BMC Neurology

Table 5 Partial correlations between ventricular ratio measures, disease parameters and cognition in MS patients ^a

From: Decision-making under explicit risk is impaired in multiple sclerosis: relationships with ventricular width and disease disability

	FHR	ICR	TVR (log)
Disease duration	0.27	0.31	0.32
Disease duration	p = 0.17	p = 0.11	p = 0.11
EDSS	0.13	0.34	0.38
EDSS	p = 0.52	p = 0.09	p = 0.049
Processing speed	−0.15	−0.57	−0.53
Processing speed	p = 0.46	p = 0.002 ^b	p = 0.005 ^b
Memory	−0.01	0.003	−0.12
Memory	p = 0.98	p = 0.99	p = 0.57
Executive functions	0.13	−0.01	0.04
Executive functions	p = 0.52	p = 0.97	p = 0.83
Global cognitive function	0.02	−0.21	−0.23
Global cognitive function	p = 0.92	p = 0.30	p = 0.26
GDT net-score	0.03	−0.42	−0.52
GDT net-score	p = 0.88	p = 0.03	p = 0.007 ^b
GDT strategy shifts (log)	−0.34	−0.02	0.01
GDT strategy shifts (log)	p = 0.09	p = 0.93	p = 0.98

Abbreviations:EDSS Expanded Disability Status Scale; FHR Frontal horn ratio (cm); GDT Game-of-Dice Task; ICR Intercaudate ratio (cm); TVR Third ventricle ratio (cm).
^a Partial correlations with disease duration and EDSS controlled for age, gender, scan site, and scanner model (df = 25). Partial correlations with cognitive composite scores and GDT-scores additionally controlled for time between MR scan and test date (df = 24).
^b p < 0.05, corrected by False-Discovery Rate [42].

Back to article page

ISSN: 1471-2377

Contact us

General enquiries: journalsubmissions@springernature.com