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Fig. 2 | BMC Neurology

Fig. 2

From: Robust disruptions in electroencephalogram cortical oscillations and large-scale functional networks in autism

Fig. 2

Posterior to anterior power spectra ratio differs significantly between ASD and control groups. a Power spectra of ASD and control groups recorded at the anterior (Fp1-F7, Fp1-F3, Fp3-F4, Fp2-F8) and posterior (T5-O1, P3-O1, P4-O2, T6-O2) nodes, calculated for each 2 s epoch, and averaged over all epochs. Training group analysis (top) and validation group analysis (bottom). Dashed lines represent two standard errors of mean. Power in units of 10log10 (μV2/Hz). b Averaged power spectra ratio between posterior and anterior channels (i.e., T5-O1/Fp1-F7) averaged over epochs and computed at four locations, then averaged over subjects to create a group average for the training (top) and validation (bottom) groups. Upper and lower 95 % confidence bounds indicated by dotted blue (ASD) and dotted red (control) lines. This result motivated the creation of the peak alpha-ratio statistic (Fig. 2c). c For each epoch, the maximum values were obtained of the four power ratios, in the alpha frequency band, and averaged. These ratios were then averaged over all epochs for each subject in the ASD (blue, Asperger’s in green) and control (red) groups. The peak alpha ratio is lower in the ASD group in the training (p ≤ 0.0034) and validation data (p ≤ 0.0025). Error bars represent two standard errors of the mean

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