Skip to main content

Table 2 Psychopathological and neuropsychological results of DM1, FSHD and control subjects

From: Prevalence and correlates of apathy in myotonic dystrophy type 1

Characteristics

DM1

FSHD

Controls

N

38

19

20

Psychopathology

  Apathy, %

39.5

21.1

0

  LARS, mean (SD)

−16.9 (8,5)ba

−22.8 (6.3)

−25.4 (4.8)

  LARS-IC, mean (SD)

−1.53 (1.2)ba

−2.45 (.7)

−2.7 (.7)

  LARS-E, mean (SD)

−2.1 (1.4)a

−2.66 (1.2)

−2.9 (1.2)

  LARS-AI, mean (SD)

−2.44 (1.1)a

−2.73 (1.1)

−3.05 (.7)

  LARS-SA, mean (SD)

−1.79 (2.1)a

−2.3 (1.6)

−2.21 (1.7)

  MADRS, mean (SD)

10.3 (8.8)

7.0 (7.4)

6.1 (6.2)

  STAI-A, T score, mean (SD)

50.1 (14.1)

44.8 (11)

45.3 (9)

  STAI-B, T score, mean (SD)

53.3 (12.6)

48.7 (12.9)

47.1 (10.9)

  KFSS, mean (SD)

4.6 (1.5)a

4.8 (1.5)c

3.3 (1.0)

Neuropsychology

  MMSE, mean (SD)

27.5 (2.2)ba

28.9 (0.9)

29.3 (0.9)

  FAB, mean (SD)

15.5 (1.7)a

15.9 (1.4)

16.5 (0.95)

  Stroop word T score, mean (SD)

47.8 (6.6)

51.6 (8.9)

51.8 (7)

  Stroop color T score, mean (SD)

44.24 (8.2)

46.56 (9.8)

49.75 (6.3)

  Stroop color-word T score, mean (SD)

39.0 (9.9)ba

49.2 (7.9)

51.8 (4.9)

  Stroop interference score, mean (SD)

44.47 (8.4)ba

49.68 (6.5)

50.65 (6.6)

  TMT-A z score, mean (SD)

0.2 (0.7)ba

0.9 (0.4)

1.0 (0.5)

  TMT-B z score, mean (SD)

−0.4 (1.2)ba

0.4 (0.6)

0.4 (0.7)

  1. LARS-IC LARS Intellectual curiosity, LARS-E LARS Emotion, LARS-AI LARS Action initiation, LARS-SA LARS Self-awareness, MADRS Montgomery Asberg Depression Rating Scale, STAI-A state anxiety, STAI-B trait anxiety, KFSS Krupp fatigue severity scale, MMSE Mini Mental State Evaluation, FAB Frontal Assessment Battery, TMT Trail Making Test
  2. aSignificant difference between DM1 and Controls, p < 0.05
  3. bSignificant difference between DM1 and FSHD, p < 0.05
  4. cSignificant difference between FSHD and Controls, p < 0.05