From: Neuropathological comparisons of amnestic and nonamnestic mild cognitive impairment
 | aMCI | ||||
Area affected | Total cases | Microscopic | Lacunar | Small | Large |
 Cortical | 10 (29 %) | 8 (24 %) | 2 (6 %) | 2 (6 %) | 2 (6 %) |
 Centrum semiovale | 3 (9 %) | 2 (6 %) | 1 (3 %) | 1 (3 %) | 1 (3 %) |
 Deep nuclei | 12 (35 %) | 4 (12 %) | 9 (26 %) | 2 (6 %) | 1 (3 %) |
 Infratentorial | 14 (41 %) | 12 (35 %) | 2 (6 %) | 2 (6 %) | 1 (3 %) |
 | naMCI | ||||
Area affected | Total cases | Microscopic | Lacunar | Small | Large |
 Cortical | 3 (20 %) | 1 (7 %) | 0 | 2 (13 %) | 1 (7 %) |
 Centrum semiovale | 3 (20 %) | 0 | 2 (13 %) | 0 | 1 (7 %) |
 Deep nuclei | 3 (20 %) | 2 (13 %) | 2 (13 %) | 0 | 0 |
 Infratentorial | 3 (20 %) | 2 (13 %) | 1 (7 %) | 0 | 0 |