Effects of botulinum toxin A and/or bimanual task-oriented therapy on upper extremity activities in unilateral Cerebral Palsy: a clinical trial

Table 3 AHA units and ABILHand-Kids logits, estimated means (standard errors)

	Follow-up weeks	BITT			BoNT-A			BoNT-A additional effect
		Yes (BoNT-A + BITT and BITT-only)	No (BoNT-A-only and control)	p-value	Yes (BoNT-A + BITT and BoNT-A-only)	No (BITT-only and control)	p-value	BoNT-A + BITT	BITT-only	p-value
		n = 24	n = 11	p-value	n = 18	n = 17	p-value	n = 13	n = 11	p-value
AHA Units (SE) p-value	0	57.5 (2.2)	52.6 (3.3)		55.0 (2.7)	55.1 (2.7)		56.0 (3.0)	59.3 (3.3)
	12	59.6 (2.2)	54.2 (3.3)	0.811	55.5 (2.7)	58.3 (2.7)	0.142	56.7 (3.0)	62.7 (3.3)	0.183
	24	58.8 (2.2)	56.8 (3.4)	0.135	57.5 (2.7)	57.8 (2.8)	0.895	58.1 (3.0)	59.0 (3.3)	0.251
	overall			0.192			0.274			0.054
ABILHand-Kids Logit units (SE) p -value	0	1.301 (0.25)	1.092 (0.37)		1.210 (0.31)	1.183 (0.31)		1.204 (0.33)	1.418 (0.36)
	6	1.481 (0.25)	1.000 (0.39)	0.468	1.162 0.31)	1.319 (0.32)	0.589	1.238 (0.33)	1.772 (0.37)	0.457
	12	*2.264* (0.25)	*1.173* (0.37)	*0.041*	1.384 (0.31)	2.054 (0.31)	0.080	1.868 (0.33)	2.672 (0.36)	0.239
	18	*2.190* (0.26)	*0.796* (0.39)	*0.016*	1.297 (0.31)	1.689 (0.33)	0.341	1.859 (0.33)	2.580 (0.38)	0.340
	24	2.230 (0.25)	1.114 (0.40)	0.128	1.369 (0.31)	1.976 (0.33)	0.241	1.980 (0.33)	2.470 (0.36)	0.659
	overall			0.132			0.457			0.748

At baseline and 6, 12, 18, and 24 weeks post BoNT-A/start BITT. Significant values are in italics and bold

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