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Table 1 Baseline characteristics and vascular risk factors in patients with leukoaraiosis (LA) and control group

From: The presence of cerebral and/or systemic endothelial dysfunction in patients with leukoaraiosis - a case control pilot study

 

LA group (n = 30)

Control group (n = 30)

p-value

Age

58 years (SD 7)

55 years (SD 6)

0.08

Men

17 (56.7 %)

20 (66.7 %)

0.60

Current smoker

5 (16.7 %)

5 (16.7 %)

0.64

Hypertension

19 (63.3 %)

16 (53.3 %)

0.60

Dyslipidemia

13 (43.3 %)

16 (53.3 %)

0.61

Minor stroke/TIA

13 (43.3 %)

0 (0.0 %)

<0.01

Lacunar infarction

9 (30.0 %)

0 (0.0 %)

<0.01

Major ischaemic infarction

1 (3.3 %)

1 (3.3 %)

0.45

Focal neurological deficits

13 (43.3 %)

4 (13.3 %)

0.04

Gait disturbance

12 (40.0 %)

2 (6.7 %)

0.01

Carotid plaques

16 (53.3 %)

10 (33.3 %)

0.19

Ischaemic heart disease

3 (10.0 %)

2 (6.7 %)

0.60

Antihypertensive therapy

19 (63.3 %)

15 (50.0 %)

0.44

Statin therapy

14 (46.7 %)

9 (30.0 %)

0.29

Antiplatelet therapy

20 (66.7 %)

7 (23.3 %)

<0.01

Systolic blood pressure

145.6 mmHg (SD 20.9)

140.1 mmHg (SD 15.0)

0.25

Diastolic blood pressure

88.7 mmHg (SD 10.1)

84.2 mmHg (SD 8.9)

0.07

Body mass index

27.8 kg/m2 (SD 4.4)

29.0 kg/m2 (SD 5.4)

0.37

Intima-media thickness

0.74 mm (SD 0.11)

0.72 mm (SD 0.11)

0.52

  1. TIA indicates transient ischaemic attack; SD standard deviation