The presence of cerebral and/or systemic endothelial dysfunction in patients with leukoaraiosis - a case control pilot study

Table 4 Absolute values of parameters before and after L-arginine infusion in patients with leukoaraiosis (LA) and control group

Parameter	LA group	Control group	p-value
v_mr	53.2 cm/s (SD 14.1)	63.0 cm/s (SD 8.1)	0.002
v_ms	57.3 cm/s (SD 18.3)	72.9 cm/s (SD 9.5)	<0.001
MAP_r	103.5 mmHg (SD 19.4)	101.5 mmHg (SD 9.9)	0.63
MAP_s	106.5 mmHg (SD 20.0)	106.1 mmHg (SD 12.0)	0.93
HR_r	64/min (SD 13)	62/min (SD 12)	0.63
HR_s	71/min (SD 12)	70/min (SD 14)	0.85
CO_2r	19.1 mmHg (SD 2.8)	20.8 mmHg (SD 5.5)	0.13
CO_2s	18.6 mmHg (SD 3.1)	21.1 mmHg (SD 5.4)	0.05

CO_2r indicates partial pressure of carbon dioxide at rest; CO_2s partial pressure of carbon dioxide after L-arginine infusion, HR_r heart rate at rest, HR_s heart rate after L-arginine infusion, MAP_r mean arterial pressure at rest, MAP_s mean arterial pressure after L-arginine infusion, SD standard deviation, v_mr mean flow velocity in middle cerebral arteries at rest, v_ms mean flow velocity in middle cerebral arteries after L-arginine infusion

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