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Table 2 Distribution of social demographic, laboratory and clinical characteristics among children with seizures

From: Incidence, causes and phenotypes of acute seizures in Kenyan children post the malaria-decline period

Variable

Complex seizure (N = 1260)

Simple seizure (N = 1482)

Total (N = 2742)

Odds ratio (95 % CI)

p-value

Age: median (interquartile range (IQR))

28.4 (12.2-51.9)

27.9 (15.8-44.4)

28.1 (14.5-47.5)

1.00 (1.00-1.00)

0.171

Sex (male)

711/1263 (56 %)

856/1486 (58 %)

1567/2749 (57 %)

0.95 (0.82-1.10)

0.489

Clinical signs and symptoms

Median respiratory rate (IQR)

40 (32–50)

38 (30–47)

38 (32–48)

1.02 (1.01-1.02)

<0.001

Median heart rate (IQR)

149 (128–166)

152 (134–167)

150 (132–167)

1.00 (0.99-1.00)

0.003

WAZa

−2 (−2 - -1)

−1 (−2 - 0)

−1 (−2 - -1)

0.97 (0.92-1.03)

0.379

MUACb

14.0 (13.0-1.05)

14.5 (13.5-15.2)

14.2 (13.0-15.0)

0.92 (0.89-0.96)

<0.001

Prostration

513 (41 %)

293 (20 %)

806 (29 %)

2.67 (2.27-3.13)

<0.001

Median temperature °C (IQR)

38.0 (37.0-39.0)

38.3 (37.4-39.2)

38.2 (37.2-39.1)

0.86 (0.81-0.91)

<0.001

Temperature gradient

90/1261 (7 %)

86/1470 (6 %)

176/2731 (6 %)

1.24 (0.91-1.68)

0.173

Laboratory investigations

Median Hb levels (IQR)

10.0 (8.6-11.2)

10.1 (9.1-11.1)

10.2 (8.9-11.1)

1.02 (0.98-1.05)

0.379

Median glucose levels (IQR)

4.8 (3.8-6.1)

4.7 (3.9-5.8)

4.7 (3.8-5.9)

1.02 (0.99-1.06)

0.169

Median sodium levels (IQR)

134 (130–137)

134 (132–137)

134 (131–137)

0.99 (0.96-1.00)

0.016

Median potassium levels (IQR)

3.9 (3.5-4.3)

3.8 (3.4-4.2)

3.8 (3.4-4.2)

1.21 (1.06-1.39)

0.005

Median BCS (IQR)

4 (2–5)

5 (4–5)

5 (4–5)

0.71 (0.69-0.76)

<0.001

Median hematocrit (IQR)

31.3 (27.0-34.6)

31.5 (28.5-34.1)

31.4 (27.9-34.3)

1.00 (0.99-1.02)

0.375

Median blood oxygen saturation % (IQR)

98 (95–100)

99 (97–100)

98 (96–100)

0.96 (0.95-0.97)

<0.001

Median mean corpuscular volume (IQR)

73.4 (66.0-81.0)

72.0 (65.0-78.0)

73.0 (65.0-79.0)

1.02 (1.01-1.03)

<0.001

Median platelets (IQR)

292.0 (146.5-421.0)

314.0 (179.0-433.0)

306.0 (165.0-427.0)

1.00 (1.00-1.00)

0.032

Parasite density ≥2.5x103/μL

318/1263 (25 %)

344/1486 (23 %)

622/2749 (39 %)

1.12 (0.94-1.33)

0.215

Median parasite density (IQR)

2976 (0–165880)

0 (0–50640)

0 (0–101710)

1.00 (1.00-1.00)

0.001

Slide positive for malaria

377/1060 (36 %)

383/1332 (29 %)

760/2392 (38 %)

1.37 (1.15-1.63)

<0.001

Creatinine

45 (37–58)

50 (38–64)

47 (37–60)

1.00 (1.00-1.00)

0.382

  1. aWAZ = weight for age; bMUAC = mid-upper arm circumference BCS = Blantyre coma score; CI = confidence interval; IQR = interquartile range