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Table 1 Effects of NH replacement and DNP administration on lifetime expectancy and QALY

From: Lifetime expectancy and quality-adjusted life-year in Alzheimer’s disease with and without cerebrovascular disease: effects of nursing home replacement and donepezil administration – a retrospective analysis in the Tajiri Project

  own homes NH replacement F-values covariance
  no DNP DNP no DNP DNP NH DNP interact age sex
AD n = 25 n = 27 n = 6 n = 7      
lifetime expectancy 56.3 (44.6) 84.7 (36.3) 122.5 (59.7) 156.4 (37.8) 20.442*** 4.704* 0.002 0.873 2.482
QALY 26.4 (17.8) 47.0 (20.5) 53.1 (18.2) 75.7 (18.5) 15.123*** 11.859*** 0.000 0.854 3.738
AD with CVD n = 9 n = 14 n = 8 n = 4      
lifetime expectancy 49.9 (41.6) 77.6 (32.9) 57.5 (44.6) 119.0 (46.2) 2.207 7.861** 1.034 0.265 0.364
QALY 30.4 (21.3) 41.9 (16.1) 30.8 (27.1) 54.4 (29.4) 0.74 3.608 0.65 0.077 2.162
  1. Two-way ANOVAs with the covariance of age and gender were performed
  2. *p < 0.05, **p < 0.01, ***p < 0.001
  3. AD Alzheimer's disease, CVD cerebrovascular diseases, QALY quality-adusted life-year
  4. DNP donepezil, NH nursing home