Table 2 Comparison of clinical and biochemical characteristics between surviving and non-surviving patients with traumatic brain injury
From: Serum caspase-3 levels and mortality are associated in patients with severe traumatic brain injury
Survivors (n = 81) | Non-survivors (n = 31) | P-value | |
|---|---|---|---|
Age (years) | 46 (27–60) | 63 (53–75) | <0.001 |
APACHE-II score | 18 (15–22) | 26 (24–29) | <0.001 |
aPTT (seconds) | 28 (25–31) | 29 (25–36) | 0.86 |
Bilirubin (mg/dl) | 0.50 (0.40–0.80) | 0.70 (0.58–0.95) | 0.045 |
Caspase-3 (ng/ml) | 0.11 (0.10–0.18) | 0.23 (0.10–0.46) | 0.003 |
CPP (mmHg) | 68 (57–70) | 61 (54–69) | 0.48 |
Creatinine (mg/dl) | 0.80 (0.63–1.00) | 0.80 (0.70–1.10) | 0.44 |
Fibrinogen (mg/dl) | 366 (283–448) | 360 (269–520) | 0.32 |
Glasgow Coma Scale score | 7 (5–8) | 3 (3–6) | <0.00171 |
Glycemia (g/dL) | 139 (122–167) | 160 (134–189) | 0.08 |
Hemoglobin (g/dL) | 11.4 (10.2–13.0) | 11.9 (9.8–13.1) | 0.87 |
ICP (mmHg) | 15 (14–20) | 25 (13–34) | 0.28 |
INR | 1.11 (1.00–1.21) | 1.12 (1.03–1.40) | 0.29 |
ISS | 25 (25–29) | 25 (25–29) | 0.80 |
Lactic acid (mmol/L) | 1.70 (1.10–2.50) | 2.40 (1.30–4.60) | 0.06 |
Leukocytes *103/mm3 | 14.5 (10.3–19.0) | 16.3 (9.8–22.7) | 0.46 |
PaO2 (mmHg) | 148 (110–203) | 133 (98–180) | 0.33 |
PaO2/FI02 ratio | 336 (240–400) | 274 (173–393) | 0.11 |
Platelets *103/mm3 | 184 (134–244) | 180 (125–237) | 0.52 |
Sodium (mEq/L) | 140 (138–143) | 142 (138–148) | 0.19 |
Temperature (°C) | 37.0 (36.0–37.3) | 36.0 (35.0–37.0) | 0.12 |