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Protocol of a randomised delayed-start double-blind placebo-controlled multi-centre trial for Levodopa in EArly Parkinson’s disease: the LEAP-study

  • Constant V. M. Verschuur1Email author,
  • S. R. Suwijn1,
  • B. Post2,
  • M. Dijkgraaf3,
  • B. R. Bloem2,
  • J. J. van Hilten4,
  • T. van Laar5,
  • G. Tissingh6,
  • G. Deuschl7,
  • A. E. Lang8,
  • R. J. de Haan3 and
  • R. M. A. de Bie1
BMC Neurology201515:236

https://doi.org/10.1186/s12883-015-0491-1

Received: 28 October 2015

Accepted: 7 November 2015

Published: 19 November 2015

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Open Peer Review reports

Pre-publication versions of this article are available by contacting info@biomedcentral.com.

Original Submission
28 Oct 2015 Submitted Original manuscript
1 Nov 2015 Author responded Author comments - Constant Verschuur
Resubmission - Version 2
1 Nov 2015 Submitted Manuscript version 2
Publishing
7 Nov 2015 Editorially accepted
19 Nov 2015 Article published 10.1186/s12883-015-0491-1

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article are available by contacting info@biomedcentral.com.

You can find further information about the peer review system here.

Authors’ Affiliations

(1)
Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
(2)
Department of Neurology, Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, The Netherlands
(3)
Academic Medical Center, Clinical Research Unit, Amsterdam, The Netherlands
(4)
Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
(5)
Department of Neurology, University Medical Center Groningen, Groningen, The Netherlands
(6)
Department of Neurology, Atrium-Orbis Medical Center Heerlen/Sittard, Heerlen, The Netherlands
(7)
Department of Neurology, University Medical Center Schleswig-Holstein, Kiel, Germany
(8)
The Edmond J. Safra Program in Parkinson’s Disease and Morton and Gloria Shulman Movement Disorders Center, Toronto Western Hospital, University of Toronto, Toronto, Canada

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