Table 2 Demographical and clinical characteristics of SPMS patients
Treated IFN transcriptional responders | Treated IFN transcriptional non responders | Untreated | |
|---|---|---|---|
N | 12 | 8 | 30 |
Age (years) | 52.4 ± 2.8 | 54.9 ± 1.5 | 51.3 ± 1.4 |
F (M) | 10 (2) | 6 (2) | 18 (12) |
Disease duration (years) | 12.9 ± 2.1(*)(**) | 22.3 ± 2.8 | 19.0 ± 1.5 |
EDSS | 6.3 ± 0.2(**) | 6.3 ± 0.3 | 7.2 ± 0.1 |
Time to EDSS 6 (years) | 11.4 ± 2.0 | 13.5 ± 1.4 | 12.6 ± 1.3 |
Annual EDSS change | 0.6 ± 0.1(*) | 0.3 ± 0.1 | 0.4 ± 0.1 |
Relapse rate | 0.8 ± 0.1(*)(**) | 0.4 ± 0.04 | 0.4 ± 0.05 |
Treatment duration (years) | 3.5 ± 0.8(*) | 6.4 ± 1.2 | NA |