Table 3 Studies on long-term outcome of DOC (disorders of consciousness) patients due to hypoxic or severe brain damage of different origin involving clinical neurophysiological data
Study | n | Methods | Results |
|---|---|---|---|
Zeitlhofer et al. 1991 [24] | 22 | AEP and SEP | Evoked potentials had no value for the prognosis of “apallic” patients |
Goldberg & Karazim 1998 [25] | 33 | AEP and SEP | AEP and SEP predicted outcome of MCS patients |
Howell et al. 2013 [26] | 113 | SEP | SEP did not predict outcome of hypoxic brain damage survivors |
Schorl, Valerius-Kukula & Kemmer 2014 [27] | 28 | Median SEP | Bliateral loss of SEP did not exclude recovery from severe brain damage |
Bagnato et al. 2015 [28] | 101 | EEG | Reduced EEG amplitudes and delta frequencies were associated with bad clinical outcome (UWS, MCS) |
Heinz & Rollnik 2015 [3] | 93 | EEG, flash VEP, median SEP | Prolongation of wave III (flash VEP), theta or delta EEG rhythm and N20/P25-amplitude reduction (SEP) predicted poor outcome (BI <50) |