|
Age
|
42
|
55
|
|
Sex
|
Female
|
Female
|
|
Diagnosis
|
Anti-NMDA receptor encephalitis
|
Anti-NMDA receptor encephalitis
|
|
Neuropsychological symptoms
|
|
AAAD (wrong age estimation)
|
Yes (17)
|
Yes (27)
|
|
Disorientation
|
Yes
|
Yes
|
|
Retrograde and anterograde amnesia
|
Yes
|
Yes
|
|
Neuropsychological examination
| | |
|
MMSEa
|
15/30
|
26/30
|
|
WMS-Rb
|
|
Verbal MQ
|
<50
|
94
|
|
Visual MQ
|
111
|
97
|
|
General MQ
|
71
|
94
|
|
Attention/Concentration
|
97
|
79
|
|
Delayed recognition
|
64
|
75
|
|
WAIS-IIIb
|
|
Verbal IQ
|
82
|
94
|
|
Performance IQ
|
68
|
86
|
|
Full scale IQ
|
72
|
89
|
|
Clinical examination
|
|
CSF
|
20 cells/mm3 (lymphocytes predominant) with normal protein levels
|
Normal cells, protein levels
|
|
Elevated anti-NMDA receptor antibody titres
|
Elevated anti-NMDA receptor antibody titres
|
|
Blood
|
Elevated anti-NMDA receptor antibody titres
|
Elevated anti-NMDA receptor antibody titres
|
|
Brain MRI
|
High intensity bilateral medial temporal lobe lesion (assessed by FLAIR)
|
No specific findings
|
|
123I-IMP brain perfusion SPECT
|
Increase in bilateral medial temporal lobe blood flow; decrease in right orbitofrontal region blood flow
|
Bilateral increase in medial temporal lobe and orbitofrontal region blood flow
|
|
EEG
|
Sporadic spike discharge and diffuse slow waves
|
No epileptic discharge
|
