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Fig. 4 | BMC Neurology

Fig. 4

From: Correlation of Tc-99 m ethyl cysteinate dimer single-photon emission computed tomography and clinical presentations in patients with low cobalamin status

Fig. 4

Single-photon emission computed tomography (SPECT) signal changes in relation to cobalamin replacement therapy. (a) A demented patient with no improvement in cognition after therapy [Mini-Mental State Examination (MMSE) = 12 to 11] had minimal signal regain only within temporal regions. (arrow heads; Patient #1) (b) A mildly cognitive impaired patient with improvement in cognition after therapy (MMSE = 24 to 28) had avid SPECT signal recovery within bilateral fronto-temporal regions.(arrow heads; Patient #3) (c) A patient with improvement of initial dysexecutive complaints and anxiety after therapy (MMSE = 28 to 30) had improving signals within bilateral thalamus (asterisk) and fronto-temporal regions.(arrow heads; Patient #7) (d) A mildly cognitive impaired patient with improvement in cognition after therapy (MMSE = 27 to 29) had improving perfusion within bilateral thalamus (asterisk) and temporal regions from the follow-up SPECT. (arrow heads; Patient #8)

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BMC Neurology

ISSN: 1471-2377

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