Fig. 1
From: Recurrent Nicolau syndrome associated with subcutaneous glatiramer acetate injection—a case report
a Nicolau Syndrome (NS) on left abdomen at first dermatological evaluation 2 days after onset. b Magnification of the NS lesion highlighting an erythematous, purpuric and haemorrhagic patch, at the site of the subcutaneous glatiramer acetate (GA) injection. Surrounding livedoid reticular patch as sign of vascular damage. c Three weeks after GA injection the livedoid patch disappeared. A skin necrosis induced by the cutaneous ischemia an atonic superficial wound developed thereafter