Skip to main content

Table 2 CSF parameters of 41 patients undergoing therapeutic apheresis (Freiburg study group)

From: Transient spurious intrathecal immunoglobulin synthesis in neurological patients after therapeutic apheresis

CSF analysis

 

Prior to treatment

One day after treatment

Two days after treatment

More than two days after treatment (median 14.0 days; range 3–55; SD 13.5)

n (%)

33 (80.5)

19 (46.3)

4 (9.8)

18 (43.9)

Intrathecal IgG synthesis, n (%)

0 (0.0)

9 (47.4)

0 (0.0)

0 (0.0)

Intrathecal IgA synthesis, n (%)

1 (3.1)

7 (36.8)

0 (0.0)

0 (0.0)

Intrathecal IgM synthesis, n (%)

1 (3.1)

8 (42.1)

0 (0.0)

0 (0.0)

IgG index ≥ 0.65, n (%)

6 (18.8)

18 (94.7)

1 (25.0)

1 (5.6)

OCBs predominantly in CSF, n (%)

1 (3.1)

0 (0.0)

0 (0.0)

1 (5.6)

  1. Abbreviations: CSF cerebrospinal fluid, IgG, IgA, and IgM immunoglobulins G, A, and M, OCBs oligoclonal bands, SD standard deviation