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Fig. 2 | BMC Neurology

Fig. 2

From: Atorvastatin in improvement of cognitive impairments caused by amyloid β in mice: involvement of inflammatory reaction

Fig. 2

ATV ameliorates spatial cognitive deficits in Aβ25–35-mice. a Hidden-platform test in Morris water maze. Each point represents group mean latency (sec) to reach the hidden-platform in control mice (control), ATV-treated control mice (control/ATV, n = 8), Aβ25–35-mice (n = 8) and ATV-treated Aβ25–35-mice (Aβ25–35/ATV, n = 8). **P < 0.01 vs. latency on day 1 (comparisons within each group); ## P < 0.01 vs. control mice; ++ P < 0.01 vs. Aβ25–35-mice (two-way ANOVA). b Swim speed (m/s) in Morris water maze. c In probe test, bars present the percentage of time spent in platform, opposite, right and left adjacent quadrants. *P < 0.05 vs. platform quadrant (comparisons within each group); # P < 0.05 vs. control mice; + P < 0.05 vs. Aβ25–35-mice (two-way ANOVA). d Bar graph shows group mean of alternation rate (%) in Y maze task. **P < 0.01 vs. control mice; ## P < 0.01 vs. Aβ25–35-mice (two-way ANOVA)

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