Skip to main content


Fig. 3 | BMC Neurology

Fig. 3

From: Atorvastatin in improvement of cognitive impairments caused by amyloid β in mice: involvement of inflammatory reaction

Fig. 3

ATV rescues impairment of LTP induction in Aβ25–35-mice. a Input–output function at Schaffer collateral-CA1 synapses. EPSP slopes plotted against stimulus intensity (0.1–0.9 mA) in control mice (n = 8), ATV-treated control mice (control/ATV, n = 8), Aβ25–35-mice (n = 8) and ATV-treated Aβ25–35-mice (Aβ25–35/ATV, n = 8). b Induction of LTP by HFS (100 Hz, 100 pulses). Each point represents group mean EPSP slopes expressed as percentage of baseline. A solid arrow indicates when HFS was given. c Influence of ATV on Aβ25–35-impaired LTP induction

Back to article page