Skip to main content

Advertisement

Fig. 4 | BMC Neurology

Fig. 4

From: Atorvastatin in improvement of cognitive impairments caused by amyloid β in mice: involvement of inflammatory reaction

Fig. 4

ATV inhibits the Aβ25–35-induced inflammatory responses in hippocampus. a Images of Iba-1 immunostaining in hippocampal CA1 of control mice (n = 8), ATV-treated control mice (control/ATV, n = 8), Aβ25–35-mice (n = 8) and ATV-treated Aβ25–35-mice (Aβ25–35/ATV, n = 8). Black arrows indicate Iba-1 positive cells. Scale bar = 50 μm. Or: oriens layer; Pm: pyramidal layer; Ra: radiatum layer. b Bar graphs show mean number of Iba-1 positive cells. **P < 0.01 vs. control mice; ## P < 0.01 vs. Aβ25–35-mice (one-way ANOVA). c & d Bars present mean levels of IL-1β mRNA and IL-1β protein. **P < 0.01 and *P < 0.05 vs. control mice; ## P < 0.01 and # P < 0.05 vs. Aβ25–35-mice. e & f Bar graph show mean levels of TNF-α mRNA and TNF-α protein. **P < 0.01 vs. control mice; ## P < 0.01 vs. Aβ25–35-mice

Back to article page