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Fig. 5 | BMC Neurology

Fig. 5

From: Atorvastatin in improvement of cognitive impairments caused by amyloid β in mice: involvement of inflammatory reaction

Fig. 5

Anti-dementia, anti-inflammatory and LTP protection of ATV in Aβ25–35-mice are abolished by replenishment of FPP. a Each point represents group mean latency to reach hidden-platform in Morris water maze. **P < 0.01 vs. Aβ25–35/ATV. b In probe test, bars show the percentage of time spent in platform quadrant in Control, Control/ FOH, Aβ25–35/ATV and Aβ25–35/ATV/FOH mice (8 in each group). *P < 0.05 vs. Aβ25–35/ATV. c Induction of LTP in FOH-treated control mice (n = 8) and Aβ25–35/ATV mice (n = 8). d Bar graph shows mean number of Iba-1 positive cells in control mice (n = 8) and Aβ25–35/ATV mice treated with FOH (n = 8). **P < 0.01 vs. Aβ25–35/ATV. e & f Bar graphs show mean levels of IL-1β and TNF-α mRNA. **P < 0.01 vs. Aβ25–35/ATV

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