|
Helium/oxygen
|
Argon/oxygen
|
Air/oxygen
|
Kruskall - Wallis
|
Non-ischemic sham
|
---|
Fluoro-Jade [numbers of stained cells per mm]
|
148 [140–166]
|
154 [124–199]
|
145 [138–182]
|
p = 0.83
|
0 [0–0]
|
pyknotic cells in CA1 [%]
|
53 [24–76]
|
59 [44–86]
|
80 [61–93]
|
p = 0.09
|
0 [0–1]
|
CA1 cell layer atrophy (normalized: surface/length) [mm2/mm]
|
0.065 [0.058–0.083]
|
0.074 [0.061–0.080]
|
0.061 [0.043–0.069]
|
p = 0.11
|
0.082 [0.077–0.088]
|
- Histological assessment of the hippocampus CA1 segment on day 5 shows a substantial damage after cardiac arrest, but there were no differences between the resuscitated animals. The animals in the non-ischemic sham group were not randomized, and thus indicated in italic style. These animals are not included in the main statistical analysis