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Table 2 Discriminant indices of MoCA and NINDS-CSN 5-minute protocol in detectingmoderate-severe VCI at 1-year

From: The Montreal cognitive assessment is superior to national institute of neurological disease and stroke-Canadian stroke network 5-minute protocol in predicting vascular cognitive impairment at 1 year

MoCA

NINDS-CSN 5-minute protocol

CUT-OFF

SEN

SPEC

PPV

NPV

ACC

CUT-OFF

SEN

SPEC

PPV

NPV

ACC

(A) Baseline

 21/22

0.95

0.62

0.37

0.98

0.68

9/10

0.79

0.54

0.29

0.91

0.59

 20/21

0.93

0.69

0.42

0.98

0.74

8/9

0.77

0.66

0.35

0.92

0.68

 19/20a

0.88

0.75

0.46

0.96

0.78

7/8a

0.73

0.75

0.41

0.92

0.75

 18/19

0.80

0.81

0.50

0.95

0.81

6/7

0.63

0.83

0.47

0.90

0.79

 17/18

0.70

0.84

0.51

0.92

0.81

5/6

0.43

0.95

0.69

0.88

0.85

(B) 3–6 months

 22/23

0.91

0.68

0.40

0.97

0.72

9/10

0.81

0.64

0.35

0.93

0.67

 21/22

0.89

0.74

0.45

0.97

0.77

8/9

0.74

0.77

0.43

0.92

0.76

 20/21a

0.83

0.80

0.50

0.95

0.81

7/8a

0.70

0.83

0.49

0.92

0.80

 19/20

0.68

0.87

0.55

0.92

0.83

6/7

0.49

0.94

0.65

0.89

0.85

 18/19

0.64

0.91

0.64

0.91

0.86

5/6

0.25

0.98

0.72

0.84

0.84

  1. aOptimal cut-off score
  2. MoCA Montreal Cognitive Assessment, NINDS-CSN National Institute of Neurological Disease and Stroke-Canadian Stroke Network, SEN sensitivity, SPEC specificity, PPV positive predicted value, NPV negative predicted value, ACC correctly classified rate