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Neuroimaging basis in the conversion of aMCI patients with APOE-ε4 to AD: study protocol of a prospective diagnostic trial

  • Guan-Qun Chen1,
  • Can Sheng1,
  • Yu-Xia Li1, 3,
  • Yang Yu1,
  • Xiao-Ni Wang1,
  • Yu Sun1,
  • Hong-Yan Li1, 4,
  • Xuan-Yu Li1,
  • Yun-Yan Xie1 and
  • Ying Han1, 2Email author
BMC NeurologyBMC series – open, inclusive and trusted201616:64

Received: 23 March 2016

Accepted: 5 May 2016

Published: 12 May 2016

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Open Peer Review reports

Pre-publication versions of this article are available by contacting

Original Submission
23 Mar 2016 Submitted Original manuscript
Author responded Author comments
Resubmission - Version 2
Submitted Manuscript version 2
Author responded Author comments
Resubmission - Version 3
Submitted Manuscript version 3
5 May 2016 Editorially accepted
12 May 2016 Article published 10.1186/s12883-016-0587-2

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article are available by contacting

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Authors’ Affiliations

Department of Neurology, XuanWu Hospital of Capital Medical University, Beijing, China
Center of Alzheimer’s Disease, Beijing Institute for Brain Disorders, Beijing, China
Department of Neurology, Tangshan Gongren Hospital, Tangshan, China
Department of Neurology, Civil Aviation General Hospital, Beijing, China