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A randomized double-blind multi-center trial of hydrogen water for Parkinson’s disease: protocol and baseline characteristics

  • Asako Yoritaka1, 2Email author,
  • Takashi Abe3,
  • Chigumi Ohtsuka4,
  • Tetsuya Maeda5,
  • Masaaki Hirayama6,
  • Hirohisa Watanabe7,
  • Hidemoto Saiki8,
  • Genko Oyama2,
  • Jiro Fukae9,
  • Yasushi Shimo2,
  • Taku Hatano2,
  • Sumihiro Kawajiri10,
  • Yasuyuki Okuma10,
  • Yutaka Machida11,
  • Hideto Miwa11,
  • Chikako Suzuki12,
  • Asuka Kazama13,
  • Masahiko Tomiyama14,
  • Takeshi Kihara15,
  • Motoyuki Hirasawa16,
  • Hideki Shimura17 and
  • Nobutaka Hattori2
BMC NeurologyBMC series – open, inclusive and trusted201616:66

https://doi.org/10.1186/s12883-016-0589-0

Received: 21 March 2016

Accepted: 5 May 2016

Published: 12 May 2016

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Open Peer Review reports

Pre-publication versions of this article are available by contacting info@biomedcentral.com.

Original Submission
21 Mar 2016 Submitted Original manuscript
Author responded Author comments
Resubmission - Version 2
Submitted Manuscript version 2
Author responded Author comments
Resubmission - Version 3
Submitted Manuscript version 3
Publishing
5 May 2016 Editorially accepted
12 May 2016 Article published 10.1186/s12883-016-0589-0

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article are available by contacting info@biomedcentral.com.

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Authors’ Affiliations

(1)
Department of Neurology, Juntendo University Koshigaya Hospital, Koshigayashi, Japan
(2)
Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan
(3)
Department of Neurology, Abe Neurological Clinic, Iwate, Japan
(4)
Department of Neurology and Gerontology, Iwate Medical University, Iwate, Japan
(5)
Department of Neurology, Research Institute for Brain and Blood Vessels-Akita Hospital, Akita, Japan
(6)
Department of Pathophysiological Laboratory Sciences, Nagoya University Graduate School of Medicine, Aichi, Japan
(7)
Brain and Mind Research Center, Nagoya University Graduate School of Medicine, Aichi, Japan
(8)
Department of Neurology, Kitano Hospital, The Tazuke Kofukai Medical Research Institute, Osaka, Japan
(9)
Department of Neurology, Fukuoka University, Fukuoka, Japan
(10)
Department of Neurology, Juntendo University Shizuoka Hospital, Shizuoka, Japan
(11)
Department of Neurology, Juntendo University Nerima Hospital, Tokyo, Japan
(12)
Department of Diagnostic Radiology, Department of Molecular Medicine and Surgery, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden
(13)
Nozomi Hospital, Saitama, Japan
(14)
Department of Neurology, Aomori Prefectural Central Hospital, Aomori, Japan
(15)
Department of Neurology, Rakuwakai Otowa Rehabilitation Hospital, Kyoto, Japan
(16)
Department of Neurology, Tokyo Rinkai Hospital, Tokyo, Japan
(17)
Department of Neurology, Juntendo University Urayasu Hospital, Chiba, Japan

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