TY - JOUR AU - Hohlfeld, R. PY - 2009 DA - 2009// TI - Multiple sclerosis: human model for EAE? JO - Eur J Immunol VL - 39 UR - https://doi.org/10.1002/eji.200939545 DO - 10.1002/eji.200939545 ID - Hohlfeld2009 ER - TY - JOUR AU - Khan, F. AU - Amatya, B. AU - Galea, M. PY - 2014 DA - 2014// TI - Management of fatigue in persons with multiple sclerosis JO - Front Neurol VL - 5 UR - https://doi.org/10.3389/fneur.2014.00177 DO - 10.3389/fneur.2014.00177 ID - Khan2014 ER - TY - JOUR AU - Bakshi, R. PY - 2003 DA - 2003// TI - Fatigue associated with multiple sclerosis: diagnosis, impact and management JO - Mult Scler VL - 9 UR - https://doi.org/10.1191/1352458503ms904oa DO - 10.1191/1352458503ms904oa ID - Bakshi2003 ER - TY - JOUR AU - Lange, R. AU - Volkmer, M. AU - Heesen, C. AU - Liepert, J. PY - 2009 DA - 2009// TI - Modafinil effects in multiple sclerosis patients with fatigue JO - J Neurol VL - 256 UR - https://doi.org/10.1007/s00415-009-0152-7 DO - 10.1007/s00415-009-0152-7 ID - Lange2009 ER - TY - JOUR AU - Weinges-Evers, N. AU - Brandt, A. U. AU - Bock, M. AU - Pfueller, C. F. AU - Dorr, J. AU - Bellmann-Strobl, J. AU - Scherer, P. AU - Urbanek, C. AU - Boers, C. AU - Ohlraun, S. PY - 2010 DA - 2010// TI - Correlation of self-assessed fatigue and alertness in multiple sclerosis JO - Mult Scler VL - 16 UR - https://doi.org/10.1177/1352458510374202 DO - 10.1177/1352458510374202 ID - Weinges-Evers2010 ER - TY - JOUR AU - Marrie, R. A. AU - Reider, N. AU - Cohen, J. AU - Trojano, M. AU - Sorensen, P. S. AU - Cutter, G. AU - Reingold, S. AU - Stuve, O. PY - 2015 DA - 2015// TI - A systematic review of the incidence and prevalence of sleep disorders and seizure disorders in multiple sclerosis JO - Mult Scler VL - 21 UR - https://doi.org/10.1177/1352458514564486 DO - 10.1177/1352458514564486 ID - Marrie2015 ER - TY - JOUR AU - Veauthier, C. AU - Paul, F. PY - 2014 DA - 2014// TI - Sleep disorders in multiple sclerosis and their relationship to fatigue JO - Sleep Med VL - 15 UR - https://doi.org/10.1016/j.sleep.2013.08.791 DO - 10.1016/j.sleep.2013.08.791 ID - Veauthier2014 ER - TY - STD TI - Rocca MA, Meani A, Riccitelli GC, Colombo B, Rodegher M, Falini A, Comi G, Filippi M. Abnormal adaptation over time of motor network recruitment in multiple sclerosis patients with fatigue. Mult Scler. 2015:doi: 10.1177/1352458515614407. ID - ref8 ER - TY - JOUR AU - Calabrese, M. AU - Rinaldi, F. AU - Grossi, P. AU - Mattisi, I. AU - Bernardi, V. AU - Favaretto, A. AU - Perini, P. AU - Gallo, P. PY - 2010 DA - 2010// TI - Basal ganglia and frontal/parietal cortical atrophy is associated with fatigue in relapsing-remitting multiple sclerosis JO - Mult Scler J VL - 16 UR - https://doi.org/10.1177/1352458510376405 DO - 10.1177/1352458510376405 ID - Calabrese2010 ER - TY - JOUR AU - Sepulcre, J. AU - Masdeu, J. C. AU - Goni, J. AU - Arrondo, G. AU - Mendizabal, N. V. AU - Bejarano, B. AU - Villoslada, P. PY - 2009 DA - 2009// TI - Fatigue in multiple sclerosis is associated with the disruption of frontal and parietal pathways JO - Mult Scler J VL - 15 UR - https://doi.org/10.1177/1352458508098373 DO - 10.1177/1352458508098373 ID - Sepulcre2009 ER - TY - JOUR AU - Tartaglia, M. C. AU - Narayanan, S. AU - Francis, S. J. AU - Santos, A. C. AU - Stefano, N. AU - Lapierre, Y. AU - Arnold, D. L. PY - 2004 DA - 2004// TI - The relationship between diffuse axonal damage and fatigue in multiple sclerosis JO - Arch Neurol VL - 61 UR - https://doi.org/10.1001/archneur.61.2.201 DO - 10.1001/archneur.61.2.201 ID - Tartaglia2004 ER - TY - JOUR AU - Filippi, M. AU - Rocca, M. A. AU - Colombo, B. AU - Falini, A. AU - Codella, M. AU - Scotti, G. AU - Comi, G. PY - 2002 DA - 2002// TI - Functional magnetic resonance imaging correlates of fatigue in multiple sclerosis JO - Neuroimage VL - 15 UR - https://doi.org/10.1006/nimg.2001.1011 DO - 10.1006/nimg.2001.1011 ID - Filippi2002 ER - TY - JOUR AU - Gottschalk, M. AU - Kumpfel, T. AU - Flachenecker, P. AU - Uhr, M. AU - Trenkwalder, C. AU - Holsboer, F. AU - Weber, F. PY - 2005 DA - 2005// TI - Fatigue and regulation of the hypothalamo-pituitary-adrenal axis in multiple sclerosis JO - Arch Neurol VL - 62 UR - https://doi.org/10.1001/archneur.62.2.277 DO - 10.1001/archneur.62.2.277 ID - Gottschalk2005 ER - TY - JOUR AU - Flachenecker, P. AU - Bihler, I. AU - Weber, F. AU - Gottschalk, M. AU - Toyka, K. V. AU - Rieckmann, P. PY - 2004 DA - 2004// TI - Cytokine mRNA expression in patients with multiple sclerosis and fatigue JO - Mult Scler J VL - 10 UR - https://doi.org/10.1191/1352458504ms991oa DO - 10.1191/1352458504ms991oa ID - Flachenecker2004 ER - TY - JOUR AU - Achiron, A. AU - Givon, U. AU - Magalashvili, D. AU - Dolev, M. AU - Zaltzman, S. L. AU - Kalron, A. AU - Stern, Y. AU - Mazor, Z. AU - Ladkani, D. AU - Barak, Y. PY - 2015 DA - 2015// TI - Effect of Alfacalcidol on multiple sclerosis-related fatigue: A randomized, double-blind placebo-controlled study JO - Mult Scler J VL - 21 UR - https://doi.org/10.1177/1352458514554053 DO - 10.1177/1352458514554053 ID - Achiron2015 ER - TY - JOUR AU - Burgos, R. A. AU - Hancke, J. L. AU - Bertoglio, J. C. AU - Aguirre, V. AU - Arriagada, S. AU - Calvo, M. AU - Caceres, D. D. PY - 2009 DA - 2009// TI - Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms: a prospective randomized placebo-controlled trial JO - Clin Rheumatol VL - 28 UR - https://doi.org/10.1007/s10067-009-1180-5 DO - 10.1007/s10067-009-1180-5 ID - Burgos2009 ER - TY - JOUR AU - Caceres, D. D. AU - Hancke, J. L. AU - Burgos, R. A. AU - Sandberg, F. AU - Wikman, G. K. PY - 1999 DA - 1999// TI - Use of visual analogue scale measurements (VAS) to asses the effectiveness of standardized Andrographis paniculata extract SHA-10 in reducing the symptoms of common cold. A randomized double blind-placebo study JO - Phytomedicine VL - 6 UR - https://doi.org/10.1016/S0944-7113(99)80012-9 DO - 10.1016/S0944-7113(99)80012-9 ID - Caceres1999 ER - TY - JOUR AU - Caceres, D. D. AU - Hancke, J. L. AU - Burgos, R. A. AU - Wikman, G. K. PY - 1997 DA - 1997// TI - Prevention of common colds with Andrographis paniculata dried extract. A pilot double blind trial JO - Phytomedicine VL - 4 UR - https://doi.org/10.1016/S0944-7113(97)80051-7 DO - 10.1016/S0944-7113(97)80051-7 ID - Caceres1997 ER - TY - JOUR AU - Sandborn, W. J. AU - Targan, S. R. AU - Byers, V. S. AU - Rutty, D. A. AU - Mu, H. AU - Zhang, X. AU - Tang, T. PY - 2013 DA - 2013// TI - Andrographis paniculata Extract (HMPL-004) for Active Ulcerative Colitis JO - Amer J Gastroenterol VL - 108 UR - https://doi.org/10.1038/ajg.2012.340 DO - 10.1038/ajg.2012.340 ID - Sandborn2013 ER - TY - JOUR AU - Carretta, M. D. AU - Alarcon, P. AU - Jara, E. AU - Solis, L. AU - Hancke, J. L. AU - Concha, I. I. AU - Hidalgo, M. A. AU - Burgos, R. A. PY - 2009 DA - 2009// TI - Andrographolide reduces IL-2 production in T-cells by interfering with NFAT and MAPK activation JO - Eur J Pharmacol VL - 602 UR - https://doi.org/10.1016/j.ejphar.2008.11.011 DO - 10.1016/j.ejphar.2008.11.011 ID - Carretta2009 ER - TY - JOUR AU - Hidalgo, M. A. AU - Romero, A. AU - Figueroa, J. AU - Cortes, P. AU - Concha, I. I. AU - Hancke, J. L. AU - Burgos, R. A. PY - 2005 DA - 2005// TI - Andrographolide interferes with binding of nuclear factor-kappaB to DNA in HL-60-derived neutrophilic cells JO - Br J Pharmacol VL - 144 UR - https://doi.org/10.1038/sj.bjp.0706105 DO - 10.1038/sj.bjp.0706105 ID - Hidalgo2005 ER - TY - JOUR AU - Iruretagoyena, M. I. AU - Tobar, J. A. AU - Gonzalez, P. A. AU - Sepulveda, S. E. AU - Figueroa, C. A. AU - Burgos, R. A. AU - Hancke, J. L. AU - Kalergis, A. M. PY - 2005 DA - 2005// TI - Andrographolide interferes with T cell activation and reduces experimental autoimmune encephalomyelitis in the mouse JO - J Pharmacol Exp Ther VL - 312 UR - https://doi.org/10.1124/jpet.104.072512 DO - 10.1124/jpet.104.072512 ID - Iruretagoyena2005 ER - TY - JOUR AU - Wang, T. G. AU - Liu, B. AU - Zhang, W. AU - Wilson, B. AU - Hong, J. S. PY - 2004 DA - 2004// TI - Andrographolide reduces inflammation-mediated dopaminergic neurodegeneration in mesencephalic neuron-glia cultures by inhibiting microglial activation JO - J Pharmacol Exp Ther VL - 308 UR - https://doi.org/10.1124/jpet.103.059683 DO - 10.1124/jpet.103.059683 ID - Wang2004 ER - TY - JOUR AU - Das, S. AU - Gautam, N. AU - Dey, S. K. AU - Maiti, T. AU - Roy, S. PY - 2009 DA - 2009// TI - Oxidative stress in the brain of nicotine-induced toxicity: protective role of Andrographis paniculata Nees and vitamin E JO - Appl Physiol Nutr Me VL - 34 UR - https://doi.org/10.1139/H08-147 DO - 10.1139/H08-147 ID - Das2009 ER - TY - JOUR AU - Chan, S. J. AU - Wong, W. S. F. AU - Wong, P. T. H. AU - Bian, J. S. PY - 2010 DA - 2010// TI - Neuroprotective effects of andrographolide in a rat model of permanent cerebral ischaemia JO - Br J Pharmacol VL - 161 UR - https://doi.org/10.1111/j.1476-5381.2010.00906.x DO - 10.1111/j.1476-5381.2010.00906.x ID - Chan2010 ER - TY - JOUR AU - Cabrera, D. AU - Pizarro, M. AU - Solis, N. AU - Torres, J. AU - Brandan, E. AU - Arrese, M. PY - 2013 DA - 2013// TI - Effects of andrographolide in experimental non-alcoholic steatohepatitis JO - Hepatology VL - 58 UR - https://doi.org/10.1002/hep.26377 DO - 10.1002/hep.26377 ID - Cabrera2013 ER - TY - JOUR AU - Polman, C. H. AU - Reingold, S. C. AU - Banwell, B. AU - Clanet, M. AU - Cohen, J. A. AU - Filippi, M. AU - Fujihara, K. AU - Havrdova, E. AU - Hutchinson, M. AU - Kappos, L. PY - 2011 DA - 2011// TI - Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria JO - Ann Neurol VL - 69 UR - https://doi.org/10.1002/ana.22366 DO - 10.1002/ana.22366 ID - Polman2011 ER - TY - JOUR AU - Schulz, K. F. AU - Altman, D. G. AU - Moher, D. AU - Group, C. PY - 2010 DA - 2010// TI - CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials JO - BMC Med VL - 8 UR - https://doi.org/10.1186/1741-7015-8-18 DO - 10.1186/1741-7015-8-18 ID - Schulz2010 ER - TY - JOUR AU - Panossian, A. AU - Hovhannisyan, A. AU - Mamikonyan, G. AU - Abrahamian, H. AU - Hambardzumyan, E. AU - Gabrielian, E. AU - Goukasova, G. AU - Wikman, G. AU - Wagner, H. PY - 2000 DA - 2000// TI - Pharmacokinetic and oral bioavailability of andrographolide from Andrographis paniculata fixed combination Kan Jang in rats and human JO - Phytomedicine VL - 7 UR - https://doi.org/10.1016/S0944-7113(00)80054-9 DO - 10.1016/S0944-7113(00)80054-9 ID - Panossian2000 ER - TY - JOUR AU - Burgos, R. A. AU - Caballero, E. E. AU - Sanchez, N. S. AU - Schroeder, R. A. AU - Wikman, G. K. AU - Hancke, J. L. PY - 1997 DA - 1997// TI - Testicular toxicity assessment of Andrographis paniculata dried extract in rats JO - J Ethnopharmacol VL - 58 UR - https://doi.org/10.1016/S0378-8741(97)00099-8 DO - 10.1016/S0378-8741(97)00099-8 ID - Burgos1997 ER - TY - JOUR AU - Krupp, L. B. AU - LaRocca, N. G. AU - Muir-Nash, J. AU - Steinberg, A. D. PY - 1989 DA - 1989// TI - The fatigue severity scale. Application to patients with multiple sclerosis and systemic lupus erythematosus JO - Arch Neurol VL - 46 UR - https://doi.org/10.1001/archneur.1989.00520460115022 DO - 10.1001/archneur.1989.00520460115022 ID - Krupp1989 ER - TY - JOUR AU - Perez, S. AU - Hervada, X. AU - Naveira, G. AU - Silva, L. AU - Fariñas, H. AU - Vázquez, E. AU - Bacallao, J. AU - Mújica, O. PY - 2010 DA - 2010// TI - The epidat program JO - Rev Panam Salud Publica VL - 27 UR - https://doi.org/10.1590/S1020-49892010000100012 DO - 10.1590/S1020-49892010000100012 ID - Perez2010 ER - TY - STD TI - R-Development-Core-Team. R: A Language and Environment for Statistical Computing. Vienna, Austria: the R Foundation for Statistical Computing. Available online at https://www.r-project.org. Accessed 20 Dec 2015. UR - https://www.r-project.org ID - ref33 ER - TY - JOUR AU - Asano, M. AU - Finlayson, M. L. PY - 2014 DA - 2014// TI - Meta-analysis of three different types of fatigue management interventions for people with multiple sclerosis: exercise, education, and medication JO - Mult Scler Int VL - 2014 ID - Asano2014 ER - TY - JOUR AU - Branas, P. AU - Jordan, R. AU - Fry-Smith, A. AU - Burls, A. AU - Hyde, C. PY - 2000 DA - 2000// TI - Treatments for fatigue in multiple sclerosis: a rapid and systematic review JO - Health Technol Assess VL - 4 ID - Branas2000 ER - TY - JOUR AU - Peuckmann, V. AU - Elsner, F. AU - Krumm, N. AU - Trottenberg, P. AU - Radbruch, L. PY - 2010 DA - 2010// TI - Pharmacological treatments for fatigue associated with palliative care JO - Cochrane Database Syst Rev VL - 11 ID - Peuckmann2010 ER - TY - JOUR AU - Shaygannejad, V. AU - Janghorbani, M. AU - Ashtari, F. AU - Zakeri, H. PY - 2012 DA - 2012// TI - Comparison of the effect of aspirin and amantadine for the treatment of fatigue in multiple sclerosis: a randomized, blinded, crossover study JO - Neurol Res VL - 34 UR - https://doi.org/10.1179/1743132812Y.0000000081 DO - 10.1179/1743132812Y.0000000081 ID - Shaygannejad2012 ER - TY - JOUR AU - Hanken, K. AU - Eling, P. AU - Hildebrandt, H. PY - 2014 DA - 2014// TI - The representation of inflammatory signals in the brain - a model for subjective fatigue in multiple sclerosis JO - Front Neurol VL - 5 UR - https://doi.org/10.3389/fneur.2014.00264 DO - 10.3389/fneur.2014.00264 ID - Hanken2014 ER - TY - JOUR AU - Lee, K. C. AU - Chang, H. H. AU - Chung, Y. H. AU - Lee, T. Y. PY - 2011 DA - 2011// TI - Andrographolide acts as an anti-inflammatory agent in LPS-stimulated RAW264.7 macrophages by inhibiting STAT3-mediated suppression of the NF-kappaB pathway JO - J Ethnopharmacol VL - 135 UR - https://doi.org/10.1016/j.jep.2011.03.068 DO - 10.1016/j.jep.2011.03.068 ID - Lee2011 ER - TY - JOUR AU - Lu, C. Y. AU - Yang, Y. C. AU - Li, C. C. AU - Liu, K. L. AU - Lii, C. K. AU - Chen, H. W. PY - 2014 DA - 2014// TI - Andrographolide inhibits TNFalpha-induced ICAM-1 expression via suppression of NADPH oxidase activation and induction of HO-1 and GCLM expression through the PI3K/Akt/Nrf2 and PI3K/Akt/AP-1 pathways in human endothelial cells JO - Biochem Pharmacol VL - 91 UR - https://doi.org/10.1016/j.bcp.2014.06.024 DO - 10.1016/j.bcp.2014.06.024 ID - Lu2014 ER - TY - JOUR AU - Burgos, R. A. AU - Seguel, K. AU - Perez, M. AU - Meneses, A. AU - Ortega, M. AU - Guarda, M. I. AU - Loaiza, A. AU - Hancke, J. L. PY - 2005 DA - 2005// TI - Andrographolide inhibits IFN-gamma and IL-2 cytokine production and protects against cell apoptosis JO - Planta Med VL - 71 UR - https://doi.org/10.1055/s-2005-864138 DO - 10.1055/s-2005-864138 ID - Burgos2005 ER - TY - JOUR AU - Lu, W. PY - 1995 DA - 1995// TI - Prospect for study on treatment of AIDS with traditional Chinese medicine JO - J Tradit Chin Med VL - 15 ID - Lu1995 ER - TY - JOUR AU - Penner, I. K. AU - Raselli, C. AU - Stocklin, M. AU - Opwis, K. AU - Kappos, L. AU - Calabrese, P. PY - 2009 DA - 2009// TI - The Fatigue Scale for Motor and Cognitive Functions (FSMC): validation of a new instrument to assess multiple sclerosis-related fatigue JO - Mult Scler VL - 15 UR - https://doi.org/10.1177/1352458509348519 DO - 10.1177/1352458509348519 ID - Penner2009 ER -