Multimodal evoked potentials for functional quantification and prognosis in multiple sclerosis

BMC Neurology

Table 3 Clinical and EP data ranked according to their relative progression (N = 76 MS patients)

Score	T0	T1	T1–T0	p*	\( \frac{\mathrm{T}1\hbox{-} \mathrm{T}0}{\mathrm{Max}}\left(\%\right) \)
LL MEP score (/10)	3.6 (3.2)	5.5 (3.6)	1.9 (2.8)	<0.0001	18.8
Global EP score (/30)	11.5 (7.0)	14.2 (7.5)	2.7 (3.9)	<0.0001	8.9
LL SEP score (/10)	4.3 (3.3)	5.1 (3.6)	0.75 (2.0)	0.0019	7.5
UL MEP score (/10)	2.4 (2.8)	3.2 (3.3)	0.75 (2.8)	0.021	7.5
VEP score (/10)	4.2 (3.5)	4.9 (3.5)	0.61 (2.2)	0.017	6.1
EDSS (/10)	2.9 (1.1)	3.4 (1.6)	0.58 (1.1)	<0.0001	5.8
pFS (/6)	2.1 (1.1)	2.4 (1.2)	0.30 (0.91)	0.0049	5.0
vFS (/6)	0.80 (1.1)	1.1 (1.0)	0.26 (0.98)	0.023	4.4
sFS (/6)	1.8 (0.93)	1.9 (0.95)	0.013 (0.97)	0.91	0.22

MS multiple sclerosis, EP evoked potentials, UL upper limb, LL lower limb, MEP motor evoked potentials, SEP somatosensory evoked potentials, VEP visual evoked potentials, EDSS expanded disability status scale, mFS pyramidal functional system, sFS sensory functional system, vFS visual functional system, Max maximal theoretical value for each individual score (i.e. 30 for Global EP score, 10 for individual EP score and EDSS, 6 for functional system)
* p-value of the evolution between T0 and T1 (median follow-up = 6.3 years)

ISSN: 1471-2377