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Table 5 Prediction models of EDSS (model 1) and annual EDSS progression (model 2) from baseline data

From: Multimodal evoked potentials for functional quantification and prognosis in multiple sclerosis

  Model 1 Model 2
EDSS EDSS progression/year
(n=100, R2=0.72) (n=100, R2=0.21)
Baseline Predictor Regression coefficient ± SE p-value Regression coefficient ± SE p-value
Intercept 2.8 ± 3.3 0.39 0.33 ± 0.59 0.58
Age (yrs) −0.0033 ± 0.014 0.81 −0.00001 ± 0.0025 0.99
Height (cm) −0.015 ± 0.021 0.48 −0.0015 ± 0.0038 0.69
Weight (kg) −0.0059 ± 0.0098 0.55 −0.0015 ± 0.0018 0.39
Sex (1= male) 0.090 ± 0.31 0.77 0.028 ± 0.056 0.62
Laterality (1=left) −0.066 ± 0.38 0.86 −0.046 ± 0.070 0.52
Phenotype (1 = SP or PP) 0.39 ± 0.46 0.40 0.010 ± 0.083 0.90
Disease duration (yrs) 0.0054 ± 0.016 0.73 0.0027 ± 0.0029 0.35
Follow-up duration (yrs) 0.036 ± 0.046 0.43 NA NA
DMT (1 = yes) 0.18 ± 0.37 0.63 0.057 ± 0.066 0.39
EDSS 0.75 ± 0.13 <0.0001 −0.035 ± 0.025 0.16
EP Score 0.082 ± 0.018 <0.0001 0.012 ± 0.0034 0.0006
  1. EDSS expanded disability status scale; R 2 multiple determination coefficient, SE standard error, SP secondary progressive, PP primary progressive, DMT disease-modifying therapy during the follow-up, EP evoked potentials, NA not applicable. Baseline predictors with p-value < 0.05 are highlighted in bold